Abstract:Multi-rate steady-state averaging deconvolution (MSAD) is a newly developed method to restore the transient auditory evoked-potential (AEP) from the auditory steady-state responses (ASSRs) based on superposition hypothesis. This method requires that the variation of stimulus rates impose no substance influence on the response so that the model is applicable and viable. In this study, we recorded eight ASSRs from 20 subjects of 40-Hz average rate (from 27.2 Hz to 57.1 Hz), from which the transient AEP can be derived by the MSAD method. The AEP was then used to synthesize the ASSRs at the same recording rates. By comparing them with the recorded ASSRs, we examined the differences on the featured waves and the ASSR morphology. Results showed the peak-peak amplitudes of V-Na and the latencies of wave-Vs were close, and no statistic difference between recorded ASSR and synthetic ASSR at 36.8 and 39.1 Hz, whereas the minimum relative error of 7.95% was achieved at 36.8 Hz ASSR. It can be concluded that the stimulus rate has little effect on the responses within these range, which justifies the applicability of the MSAD method.
林霖, 谭小丹, 王涛. 对40 Hz听觉稳态反应应用线性叠加条件的评估[J]. 中国生物医学工程学报, 2016, 35(3): 278-283.
Lin Lin, Tan Xiaodan, Wang Tao. An Assessment of Linear Superposition Conditions for 40 Hz Auditory Steady-State Responses. Chinese Journal of Biomedical Engineering, 2016, 35(3): 278-283.
[1] Regan D. Comparison of transient and steady-state methods [J]. Ann NY Acad Sci, 1982, 388:45-71. [2] Galambos R, Makeig S, et al. A 40-Hz auditory potential recorded from the human scalp [J]. Psychology, 1981, 78(4): 2643-2647. [3] Delgado RE, Özdamar O. Deconvolution of auditory evoked potentials obtained at high stimulus rates. [J]. The Journal of the Acoustical Society of America, 2004, 115:1242-1251. [4] Özdamar O, Bohórquez J. Signal to noise ratio and frequency analysis of continuous loop averaging deconvolution (CLAD) of overlapping evoked potentials [J]. The Journal of the Acoustical Society of America, 2006, 119:429-438. [5] Özdamar O, Delgado RE, Yavuz E, et al. Deconvolution of auditory evoked potentials obtained at high stimulus rates[C] // First International IEEE EMBS Conference on Neural Engineering. Capri: IEEE, 2003: 285-288. [6] Mcneer RR, Bohórquez J, Özdamar O. Influence of auditory of auditory stimulation rates on evoked potentials during general anesthesia: relation between the transient auditory auditory middle-latency response and the 40-Hz auditory steady state response [J]. Anesthesiology, 2009, 110(5): 1024-1035. [7] Gutschalk A, Mase R, Roth R, et al. Deconvolution of 40 Hz steady-state fields reveals two overlapping source activities of the human auditory cortex[J]. Clinical Neurophysiology, 1999, 110(5): 856-868. [8] Wang Tao, Zhan Changan, Yan Gang, et al. A preliminary investigation of the deconvolution of auditory evoked potentials using a session jittering paradigm [J]. Journal of Neural Engineering, 2013, 10(2): 026023. [9] 朱程,王涛,黄江华,等. 40 Hz瞬态听觉诱发电位中潜伏期成分的引出分析[J]. 中国生物医学工程学报, 2013.32(5):539-545. [10] 冯洁婷, 颜刚, 王涛,等. Tikhonov正则化参数选择对高速率刺激听觉诱发电位重建的影响[J]. 航天医学与医学工程, 2012. 25(1): 54-60. [11] 冯洁婷, 颜刚, 鲜星宇,等. L-曲线估计正则化参数对高速率刺激听觉诱发电位重建的影响[J]. 中国生物医学工程学报, 2012, 31(2): 237-246. [12] Tikhonov AN, Arsenin VY. Solutions of Ill-Posed Problems [M]. New York: Wiley, 1977. [13] Hansen PC, Voldgade O. The truncated SVD as a method for regularization BIT Numer[J]. Math, 1987, 27:1487-1503. [14] Tucker DA, Dietrich S,Harris S. Effects of stimulus rate and gender on the Auditory evoked Middle Latency Response [J]. Journal of the American Academy of Auditory, 2002, 13:146-155. [15] Özdamar O, Krausa N. Auditory middle-latency response in humans [J]. Audiology, 1983, 22:34-49. [16] Bohórquez J, Özdamar O. Generation of the 40-Hz auditory steady-state response (ASSR) explained using convolution [J]. Clinical Neurophysiology, 2008,119: 2598-2607. [17] Özdamar O, Bohórquez J. Suppression of the Pb (P1)component of the auditory middle latency response with contralateral msaking[J]. Clinical Neurophysiology, 2008,119: 1870-1880. [18] Hari R, Hamalainen M, Joutsiniemi SL. Neuromagnetic steady-state responses to auditory stimuli [J]. J Acoustic Soc Am, 1989, 86: 1033-1039.