Effects of Transcranial Direct Current Stimulation on Features of Human Balance Brain Network
Cai Hongwei1, Luo Zhizeng1#*, Shi Hongfei2
1(Institute Intelligent Control and Robotics, School of Automation, Hangzhou Dianzi University, Hangzhou 310018, China) 2(The Fourth Affiliated Hospital Zhejiang University School of Medicine,Jinhua 322000, Zhejiang, China)
Abstract：Transcranial electrical stimulation is a neuromodulation technology with wide application potential, which still remains on the external manifestation in the research of human balance, and mechanisms of influence on the neuromodulation of human balance have not been clear yet. Brain functional network is an effective means to understand brain function and regulation mechanism. In this work, a method to study the features of human balanced brain network by transcranial electrical stimulation was proposed. There were 24 subjects recruited to apply sham/ anodal/cathodal transcranial direct current stimulation (tDCS) in the primary motor cortex, and the planar center of pressure (COP) and EEG data were collected while standing with eyes closed, and the features of COP and the features of network including average degree, clustering coefficient, path length and global efficiency were compared and analyzed. Experimental results showed that anodal tDCS reduced human shaking frequency. The average degree, clustering coefficient, path length and global efficiency after sham tDCS and anodal tDCS were 6.11±1.21 and 0.51±0.07, 1.85±0.16 and 0.64±0.05, 7.46±1.05, 0.61±0.06, 1.66±0.14, 0.69±0.04, respectively. There were significant differences in all groups (P<0.05). The shaking frequency was increased by cathodal tDCS, and the average degree, clustering coefficient, path length and global efficiency were 5.51±1.33, 0.43±0.07, 1.95±0.16 and 0.62±0.04, respectively, which were significantly different from those after sham tDCS (P<0.05). These results showed that anodal tDCS effectively activated the activity of motor cortex, enhanced the inter-interval connection of the whole brain network, and improved the balance ability of the human; while cathodal tDCS inhibited the activity of the motor cortex, and the balance ability of the human was weakened.
作者简介: #中国生物医学工程学会会员(Member, Chinese Society of Biomedical Engineering)
引用本文:
蔡宏伟, 罗志增, 史红斐. 经颅直流电刺激对人体平衡脑网络特征的影响研究[J]. 中国生物医学工程学报, 2023, 42(4): 394-402.
Cai Hongwei, Luo Zhizeng, Shi Hongfei. Effects of Transcranial Direct Current Stimulation on Features of Human Balance Brain Network. Chinese Journal of Biomedical Engineering, 2023, 42(4): 394-402.
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