Research and Novel Application on MR Diffusion Kurtosis Imaging
Sha Miao1, Zhao Xin1#*, Chen Yuanyuan1, Wang Weiwei1, Zhou Peng1#, Ni Hongyan2, Ming Dong1#
1(School of Precision Instrument and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, China) 2(Department of Radiology, Tianjin First Center Hospital, Tianjin 300192, China)
Abstract：As an emerging technology of diffusion MRI, diffusion kurtosis imaging (DKI) introduces forth-order tensor to quantify the degree to non-Gaussian water diffusion in biologic tissues. Additional kurtosis information on the water diffusion properties could be more sensitive to tissue microstructure in the brain. This paper introduced diffusion kurtosis model, data acquisition parameters, model fitting and microstructural model based on DKI to reveal research development and clinical application of DKI model. Meanwhile, limitations of DKI model and prospect of its profound influence on all aspects of neural radiology were discussed as well.
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