Research Progress on Sensing Technology and Clinical Application of Digestive Tract PhysiologicalParameters Wireless Capsule
Hu Xiaoyu1, Feng Jie1, Zhao Xiaxia1, Huang Xiaojun1,2*
1(Department of Gastroenterology, Second Hospital of Lanzhou University, Lanzhou 730030, China) 2(Medical Engineering Research and Development Center of Gansu Province, Lanzhou 730030, China)
Abstract：The physiological mechanism of the digestive tract has been high-profile for a long time. With the rapid development of sensors and detection technologies, there has been an increasing focus on the gastrointestinal physiological parameters wireless capsules and attempts to expand their indications to solve the problem that various physiological information in the human gastrointestinal tract can be obtained difficulty. The information related to gastrointestinal motility can be acquired by micro-devices with integrated sensors, thus the dynamic curve and even peristaltic model of the digestive tract can be established to provide clinical evidence for the diagnosis and mechanism exploration of functional gastrointestinal diseases. In this review, firstly, the types, principles, and research progress of sensors applied in wireless capsules were described according to the different types of detection information. Next, a summary of the current clinical applications research status of the wireless capsules has been made, including the detection of pH, temperature, and pressure, as well as the continuous fixed-point monitoring of the physical and chemical digestive tract environment. The functional expansion research of the wireless capsules was introduced as well, such as the detection of intestinal gases, flora, digestive enzymes, etc. Finally, the R&D challenges and corresponding strategies of the wireless capsules for physiological parameters were discussed, providing useful reference information for future research in this field.
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