Cerebral Cortex Functional Connection Analysis of Magnetic Stimulation at Neiguan Acupoint (PC6) Based on Complex Network
Yin Ning1,2#, Dai Yangyang1,2, Sheng Hui1,2, Xu Guizhi1,2#*
1(State Key Laboratory of Reliability and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin 300130, China) 2(Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability of Hebei Province, Hebei University of Technology, Tianjin 300130, China)
Abstract：Combined with magnetic stimulation technique, electroencephalogram (EEG) and traditional acupoint theory, the coordinated regulation process of cerebral cortex functional network evoked by acupoint stimulation was studied in this work. The EEG signals in resting state and magnetic stimulation at Neiguan (PC6) acupoint of 14 healthy subjects were reconstructed to determine the brain network nodes, using the group independent component analysis and standard low-resolution brain electromagnetic tomography. The correlation coefficient between the alpha-band power spectrums was calculated by the short-time Fourier transform and the cross-correlation method. Based on t-test and false discovery rate correction (FDR) the brain network connection edges (P<0.05, FDR corrected) were constructed. The functional connections of cerebral cortex were analyzed. Results showed that the functional connections of nodes in brain areas related to movement decreased by 22.9%, the functional connections of nodes in brain areas associated with emotion and memory increased by 93.8%, the functional connections of nodes in the frontal lobe and temporal lobe increased by 21.2% during magnetic stimulation. The topological structure changes of the cerebral cortex functional network caused by magnetic stimulation at PC6 are consistent with the function of the acupoint. This study provides new clues for revealing the mechanism of acupoint regulation.
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