Abstract：Multiscale permutation entropy was utilized to analyze complexity measure of resting state MEG recordings from schizophrenic patients and healthy control subjects in this paper. By comparing and analyzing the mean value of multiscale permutation entropy between schizophrenia and control subjects, we found that multiscale permutation entropy of the schizophrenia′s MEG in 93.82% channels was higher than that of the control subjects. In addition, the experimental result showed that multiscale permutation entropy of schizophrenics′ MEG recordings had significant differences in 19 channels (P<0.05, FDR correction). These channels were mainly distributed on the temporal and frontal, especially the edge region of temporal, which was consistent with the results of previous schizophrenia neuroimaging studies such as MRI and EEG. These features can be served to provide important reference for the further researches of schizophrenia pathological mechanism analysis and clinical diagnosis method.
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