Research Advances in 3D Bio-printing for Breast Cancer
Shi Panpan1,2, Zhai Weijia3, Wang Xiaofeng1,2, Zhang Yiqing1,2, Deng Lili1,2, Tang Ningning1,2, Wang Yunlong1,2,4*
1(Henan Provincial Engineering Research Center for Instant Detection, Zhengzhou 450100, China) 2(Zhengzhou Technical College, Zhengzhou 450121, China) 3(The Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China) 4(Henan Provincial Engineering Research Center for Biotechnology, Zhengzhou 450001, China)
Abstract：Breast cancer is one of the most common malignant tumors among women worldwide, and its high heterogeneity poses significant challenges for precision therapy in medical research. The 3D bioprinting technology enables precise spatial control of cells, biomaterials, and biomolecules at the microscale, constructing complex tissue structures or microenvironments, thereby providing a novel platform for precision therapy of breast cancer. This paper systematically reviewed recent advancements in 3D bioprinting applications for breast cancer research, with particular focus on its implementation in constructing in vitro tumor models, guiding precision drug therapy, facilitating personalized surgical planning, and post-operative breast reconstruction. Current technical challenges and future development directions were critically discussed. This review aimed to provide valuable references for researchers and clinicians engaged in precision therapy of breast cancer for promoting the clinical translation of 3D bioprinting technology in breast cancer treatment.
石盼盼, 翟维佳, 王晓峰, 张怡青, 邓黎黎, 汤宁宁, 王云龙. 生物3D打印技术在乳腺癌研究与治疗中的研究进展[J]. 中国生物医学工程学报, 2025, 44(6): 748-758.
Shi Panpan, Zhai Weijia, Wang Xiaofeng, Zhang Yiqing, Deng Lili, Tang Ningning, Wang Yunlong. Research Advances in 3D Bio-printing for Breast Cancer. Chinese Journal of Biomedical Engineering, 2025, 44(6): 748-758.
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