小口径人工血管构建研究现状与展望

doi:10.3969/j.issn.0258-8021. 2016. 03.014

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Abstract There is a growing demand of vascular grafts for clinical treatment, the problem is also general, and especially the small-diameter vascular’s incidence rate of restenosis is high after implantation. Tissue engineering has been applied in the fabrication of vascular grafts, the bionic and tissue regeneration. Tissue engineered vascular graft have been developed as alternative to autografts, but the low patency limit their clinical application. In this review, we introduced the latest develepment of vascular grafts in both domestic and foreign research, including the fabrication and modification of artificial vascular scaffolds, the role of cellular and extracellular microenvironment in artificial vascular reconstruction. We also discussed the problems and prospects of the directions for the future research of tissue engineered vascular grafts.

Key words： vascular graft bioactive substances vascular engineering restenosis

Received: 18 December 2015

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R318

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	Articles by authors
	Jiang Li
	Chen Siyuan
	Wang Yuanyuan
	Wang Shufang

Cite this article:

Jiang Li,Chen Siyuan,Wang Yuanyuan, et al. Progress and Prospect of Small-Diameter Vascular Grafts Research[J]. Chinese Journal of Biomedical Engineering, 2016, 35(3): 357-364.

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021. 2016. 03.014 OR http://cjbme.csbme.org/EN/Y2016/V35/I3/357

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