冠脉支架内再狭窄的血流动力学研究进展

doi:10.3969/j.issn.0258-8021. 2015. 03.013

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Abstract Coronary stent restenosis is a high incidence and severe medical event. Local hemodynamic factors, wall shear stress (WSS) in particular, critically affect the formation, progression and heterogeneity of atherosclerotic plaque. Emerging preclinical and clinical in vivo evidences now suggest that WSS may also contribute to the occurrence of stent restenosis. This review starts from the formation mechanism of instent restenosis, analyzes the mechanism of mechanical environment in coronary stent restenosis and elaborates the computational fluid dynamics (CFD) research progress in haemodynamics associated with instent restenosis in detail.

Key words： coronary wall shear stress stent restenosis computational fluid dynamics

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021. 2015. 03.013 OR http://cjbme.csbme.org/EN/Y2015/V34/I3/354

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