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Chinese Journal of Biomedical Engineering  2021, Vol. 40 Issue (1): 107-117    DOI: 10.3969/j.issn.0258-8021.2021.01.12
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Advances in Exhaled Breath Analysis: A Potential Screening Tool and its Application in Clinical Diagnosis
Zhu Xingzhuo, Zhao Dongbujia, Zheng Yixuan, Ning Xuan, Yuan Hao, Wu Chunsheng*
(Institute of Medical Engineering, Department of Biophysics, School of Basic Medical Sciences, Xi'an Jiaotong University,Xi'an 710061, China)
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Abstract  Exhaled breath analysis is a diagnostic tool that provides useful information for early clinical diagnosis by detecting the changes of characteristic components in human breath. Compared with traditional methods, exhaled breath analysis provides a non-invasive, rapid and easy screening tool that has promising potential applications in early diagnosis and screening of diseases. However, there are still some problems in the clinical applications of this technique. This review summarized three aspects, including exhaled breath collection, multiple detection methods and the application of this technology in the diagnosis of various diseases. At last, we discussed the limitations and prospects of exhaled breath analysis.
Key wordsexhaled breath analysis      volatile organic compounds      non-invasive      early diagnosis      screening     
Received: 11 April 2020     
PACS:  R318  
Corresponding Authors: *E-mail: wuchunsheng@xjtu.edu.cn   
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Zhu Xingzhuo
Zhao Dongbujia
Zheng Yixuan
Ning Xuan
Yuan Hao
Wu Chunsheng
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Zhu Xingzhuo,Zhao Dongbujia,Zheng Yixuan, et al. Advances in Exhaled Breath Analysis: A Potential Screening Tool and its Application in Clinical Diagnosis[J]. Chinese Journal of Biomedical Engineering, 2021, 40(1): 107-117.
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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2021.01.12     OR     http://cjbme.csbme.org/EN/Y2021/V40/I1/107
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