舌下微循环显微影像监测及其应用研究进展

doi:10.3969/j.issn.0258-8021.2021.01.11

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Abstract Microcirculatory lesions are the key link leading to tissue hypoperfusion. Monitoring of microcirculatory lesions is very important in severe diseases. The tongue body is rich in microvessels, in which the sublingual microcirculation presents a reticular structure, reflecting the state of microcirculation in living tissue, and is an ideal and important site for clinical microcirculation monitoring and microcirculation detection in living animals. The equipment, index system, application, clinical significance and future prospect of sublingual microcirculation microimage monitoring were reviewed in this article. Firstly, we introduced the monitoring equipment, including the composition of the equipment, the types of optical technology adopted by the probe, the image processing algorithm adopted by the host, and the fixed form of the probe. Secondly, the index system of sublingual microcirculation microimage monitoring was summarized, including the perfusion quality index, vascular density index and perfusion heterogeneity index. Next, an example was given to illustrate the clinical and experimental applications, including the study on the relationship between diseases and microcirculation in clinical practice, the study on the relationship between drugs and microcirculation, and the study on the relationship between visceras' microcirculation using sublingual microcirculation microimage monitoring technology. Finally, the significance of clinical diagnosis, treatment and research were discussed, and the technical improvement, development and application direction are prospected.

Key words： sublingual microcirculation monitoring in microimage microcirculation disorder severe disease

Received: 24 December 2019

PACS:

R318

Corresponding Authors: *E-mail: gmning@zju.edu.cn

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	Articles by authors
	Jiang Sheng
	Li Peilun
	Ning Gangmin

Cite this article:

Jiang Sheng,Li Peilun,Ning Gangmin. Progress of Sublingual Microcirculation Microimage Monitoring and Application[J]. Chinese Journal of Biomedical Engineering, 2021, 40(1): 99-106.

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2021.01.11 OR http://cjbme.csbme.org/EN/Y2021/V40/I1/99

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