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| Cortico-Muscular Coupling Analysis Based on Cumulative Spike Sequence of Motor Unit |
| Su Jiahao1, She Qingshan1,2*, Zhang Jianhai3, Ma Yuliang1,2, Fan Yingle1 |
1(School of Automation, Hangzhou Dianzi University, Hangzhou 310018, China)
2(International Joint Research Laboratory for Autonomous Robotic System, Hangzhou 310018, China)
3(Key Laboratory of Brain Machine Collaborative Intelligence of Zhejiang Province, Hangzhou 310018, China) |
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Abstract Cortico-muscular coupling can reflect the connection between cerebral cortex and muscle in sensorimotor. This paper proposed a new cortico-muscular coupling analysis method, that is utilizing EEG and cumulative spike train (CST) obtained after the decomposition of the motor unit to linearly transmit the neural drive for coherence analysis, quantitatively assessing cortico-muscular coupling and common synaptic input of neurons under different frequency band at different contraction force levels during upper limb grasping. The synchronous EEG and sEMG data of flexor digitorum superficialis (FDS) and flexor carpi ulnaris (FCU) were measured and analyzed in 10 healthy subjects. Results showed that both frequency band (F (4, 8)=337.2, P<0.01) and contractile force level (F (2,8)=12.15, P<0.01) had significant effects on the intermuscular coupling during upper limb grasping exercise, especially in β and α band. At 30% MVC, the mean coherence of β frequency band was 0.23 ± 0.10, and that of α frequency band was 0.47 ± 0.02. The synaptic input controls the level of contraction force. Cortico-muscular coupling was relatively low. The highest coupling strength was in β band with a coherence value of 0.12 ± 0.01 at 30% MVC. The CST brain muscle coupling analysis can reflect the coupling characteristics and common synaptic inputs of various frequency bands and contraction levels between brain muscles, providing a new method for brain muscle coupling analysis.
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Received: 11 October 2022
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Corresponding Authors:
*E-mail: qsshe@hdu.edu.cn
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