经颅直流电刺激对人体平衡脑网络特征的影响研究

doi:10.3969/j.issn.0258-8021.2023.04.002

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Abstract Transcranial electrical stimulation is a neuromodulation technology with wide application potential, which still remains on the external manifestation in the research of human balance, and mechanisms of influence on the neuromodulation of human balance have not been clear yet. Brain functional network is an effective means to understand brain function and regulation mechanism. In this work, a method to study the features of human balanced brain network by transcranial electrical stimulation was proposed. There were 24 subjects recruited to apply sham/ anodal/cathodal transcranial direct current stimulation (tDCS) in the primary motor cortex, and the planar center of pressure (COP) and EEG data were collected while standing with eyes closed, and the features of COP and the features of network including average degree, clustering coefficient, path length and global efficiency were compared and analyzed. Experimental results showed that anodal tDCS reduced human shaking frequency. The average degree, clustering coefficient, path length and global efficiency after sham tDCS and anodal tDCS were 6.11±1.21 and 0.51±0.07, 1.85±0.16 and 0.64±0.05, 7.46±1.05, 0.61±0.06, 1.66±0.14, 0.69±0.04, respectively. There were significant differences in all groups (P<0.05). The shaking frequency was increased by cathodal tDCS, and the average degree, clustering coefficient, path length and global efficiency were 5.51±1.33, 0.43±0.07, 1.95±0.16 and 0.62±0.04, respectively, which were significantly different from those after sham tDCS (P<0.05). These results showed that anodal tDCS effectively activated the activity of motor cortex, enhanced the inter-interval connection of the whole brain network, and improved the balance ability of the human; while cathodal tDCS inhibited the activity of the motor cortex, and the balance ability of the human was weakened.

Key words： transcranial direct current stimulation balance brain network

Received: 29 March 2022

PACS:

R318

Corresponding Authors: ^*E-mail:luo@hdu.edu.cn

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	Cai Hongwei
	Luo Zhizeng
	Shi Hongfei

Cite this article:

Cai Hongwei,Luo Zhizeng,Shi Hongfei. Effects of Transcranial Direct Current Stimulation on Features of Human Balance Brain Network[J]. Chinese Journal of Biomedical Engineering, 2023, 42(4): 394-402.

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2023.04.002 OR http://cjbme.csbme.org/EN/Y2023/V42/I4/394

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