基于SLM技术的表面多孔钛金属多根牙种植体的骨结合研究

doi:10.3969/j.issn.0258-8021. 2015.03.008

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Abstract The present study was to develop a multiroots dental implant (MRI) surface structure with fine osseointegration characteristics. Finite element method (FEM) was used to optimize a kind of connected pore structure; selective laser melting (SLM) technology was utilized to manufacture the MRIs. Eighteen New Zealand white rabbits were used in this study. Eighteen MRIs and 18 commercial implants with resorble blast media (RBM) treated surface were inserted into the left and right hind limb at proximal tibias. At the time point of 4, 8 and 12 weeks the rabbits were sacrificed and bone tissues with implant were collected. All specimens were scanned by microCT and then BV/TV values of two groups were obtained. After that the specimens were processed for undecalcified ground sectioning and stained by toluidine blue to observe bone formation around implant. The BV/TV value of experimental group was higher than the control group at the end of 4 weeks, and at the end of 12 weeks the value was significantly higher than control group (P < 005), the peak value was elevated up to 4783%. From the fitting curve of BV/TV value, bone mass around at MRIs were still increasing at the end of 12 weeks, while the control group had achieved a balance. Histological evaluations revealed that bone surround the MRIs were denser than those of RBM implants. At the end of 4 weeks bone tissue had grew into pore structures, and at the end of 8 weeks bone tissue were observed in the root bifurcating area. In conclusion, the multiroots dental implant with threedimensional connected pore structure surface manufactured by SLM technology enhance its initial stability, which is of great clinical value owe to its better osteogenic characteristics.
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Key words： multiroots implant SLM technique porous structure osseointegration microCT

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021. 2015.03.008 OR http://cjbme.csbme.org/EN/Y2015/V34/I3/315

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