基于多尺度特征感知的胸腔图像危及器官分割

doi:10.3969/j.issn.0258-8021.2021.06.07

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Abstract Automatic segmentation of organs at risk (OARs) in medical images is an essentialconstituent of computer-aided diagnosis, and it plays a vital role in assisting doctors to completeradiotherapy with high quality and efficiency. There are some challenges in the accuratesegmentation of OARs for thoracic CT images, including low intensity contrast, different organswith interlaced and overlap regions, and different structure without clear boundaries. In this paper,a multi-scale feature-aware encoding-decoding network (FA-Unet) was proposed to segmentOARs in thoracic CT images.To address the problem of the size difference among fourkinds of organs in the thoraciccavity, an input-aware module was designed to extract multi-scale features in four types of organs. In order to bridge the semantic gap between theencoding and decoding layers, the modified inception module was introduced to long-range skipconnections between the encoding part and the decoding part in our architecture. Furthermore,we replaced the traditional serial convolution operation with the efficient spatial pyramid(ESP) andpyramid spatial pooling (PSP) modules to make our network more lightweightand avoide over-fitting caused by insufficient data effectively. We formulated a novel lossfunction by combining Dice coefficient and cross entropy to train our network to resolve theclass imbalance in thoracic CT images. Finally, we evaluated the effectiveness of our model onthe SegTHOR data set released by ISBI in 2019, and the dataset includes 7 390 thoracic CTimages of 40 patients with lung cancer or Hodgkin's lymphoma. Experimental results showedthat Dice coefficient of each organ in thoracic CT image was 0.793 2 of esophagus, 0.935 9of heart, 0.854 9 of trachea and 0.889 0 of aorta. Hausdorff distances was 1.420 7 of esophagus,0.212 4 of heart, 0.627 3 of trachea and 0.887 0 of aorta. Experimental results verified that ourproposed model outperformed other state-of-the-arts on the segmentation results of OARs andachieved very competitive performance on small target organs.

Key words： thoracic CT image segmentation of organs at risk multi-scale feature-aware feature-aware encoding-decoding network (FA-Unet)

Received: 21 September 2020

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	Articles by authors
	Deng Shijun
	Tang Hongzhong
	Zeng Li
	Zeng Shuying
	Zhang Dongbo

Cite this article:

Deng Shijun,Tang Hongzhong,Zeng Li, et al. Segmentation of Thoracic Image Organs at Risk Based on Multi-Scale Feature-Aware[J]. Chinese Journal of Biomedical Engineering, 2021, 40(6): 701-711.

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2021.06.07 OR http://cjbme.csbme.org/EN/Y2021/V40/I6/701

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