巨噬细胞在生物材料植入反应及组织再生中的作用

doi:10.3969/j.issn.0258-8021.2017.06.016

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Abstract There is a growing demand for biomaterials in clinical therapeutics. The implantation of biomaterials might end up in failure due to post-implantation inflammation. An effective approach to induce tissue regeneration would be the modulation of the macrophages responses to the implanted biomaterials. This review summaried the origin, subtypes, expression markers and functions of macrophages. Meanwhile strategies to induce macrophages toward the role of alleviating inflammation and promoting tissue regeneration after biomaterials implantation were introduced comprehensively. Some noteworthy challenges and directions in the research on facilitating tissue regeneration through the modulation of macrophages were discussed as well.

Key words： biomaterials macrophage tissue regeneration

Received: 16 January 2017

PACS:

R318

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	Articles by authors
	Shi Jie
	Tang Di Gao
	Jingchen
	Kong Deling
	Wang Shufang

Cite this article:

Shi Jie,Tang Di Gao,Jingchen, et al. The Effect of Macrophages on the Post-Implantation Reaction of Biomaterials and Tissue Regeneration[J]. Chinese Journal of Biomedical Engineering, 2017, 36(6): 749-754.

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2017.06.016 OR http://cjbme.csbme.org/EN/Y2017/V36/I6/749

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