Abstract：The aim of this work was to study the influences of internal fixation parameters on the fracture healing between transverse and oblique fracture. The second-development of Abaqus based on Python was used for the simulation of healing process. During the simulating process, the mechanical modulation and cell differentiation were integrated. The method of orthogonal experiment was used for studying the effects of parameters on the healing process, and different parameter combinations were constructed based on the orthogonal table of L9(34). Finally, an optimal combination was selected after the analysis. Results showed that the working length of the plate was the most influential parameter, a great divergence of healing pattern between transverse and oblique fracture was found under the low level of working length, the time of healing reached 1 000 MPa for transverse fracture was shorter than that for oblique fracture. Increased working length will drive the two fracture modes to show a similar healing pattern, their healing results finally reached or over 1400 MPa at the end of 16 weeks, which meant that a suitable mechanical environment for healing process could be ensured by omitting one or two screws that were proximal to the fracture gap. The healing efficiency of both the transverse and oblique fracture was highly correlated with the choice of internal fixation parameters. Compared with transverse fracture, oblique fracture required higher standard of stability for fracture healing, therefore, more screws were needed for the oblique fracture to ensure the stability.
方润心, 纪爱敏, 陈长胜, 龙登燕, 赵仲航. 接骨板内固定参数对骨愈合过程的影响分析[J]. 中国生物医学工程学报, 2019, 38(4): 438-446.
Fang Runxin, Ji Aimin, Chen Changsheng, Long Dengyan, Zhao Zhonghang. Bone Healing Analysis of Transverse and Oblique Fracture Under Different Internal Fixation Parameters. Chinese Journal of Biomedical Engineering, 2019, 38(4): 438-446.
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