Abstract：In recent years, with microvesicles (MV) studies development, how to effectively obtain a sufficient amount of high purity microvesicles has become a big challenge in this field. Microvesicles also known as microparticles, are small vesicles that fall off from the cell membrane after cell activation, injury or apoptosis. MV with a diameter of about 100～1000 nm can interact with cells through different mechanisms and play a similar biological function as the source cells do. At the same time, MV have become a new favorite in bionic drug carrier research because of their natural membrane components and good biological transmissibility. In this paper, we summarized the principle, application and key technologies, and the existing key technologies for extraction and identification of MV, and also made prospections about MV's application in the future.
钟宇彤, 黎艳红, 林辉, 罗玉斌. 微囊泡产生及鉴定体系现状分析[J]. 中国生物医学工程学报, 2020, 39(3): 362-366.
Zhong Yutong, Li Yanhong, Lin Hui Luo Yubin. Analysis of Microvesicle Generation and Identification System. Chinese Journal of Biomedical Engineering, 2020, 39(3): 362-366.
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