Abstract：In the percutaneous coronary intervention (PCI), overlapping stents are often used to treat diffuse coronary lesions. There are many clinical studies on overlapping stents, which provide the clinical effect and efficacy of the stents. However, the interactions between stents and stents, stents and blood vessels have not been demonstrated by direct observations. The aim of this study was to investigate the changes of stent, vessel morphology and stress during stenting by analyzing the coronary stents with superimposed stents. A real diffuse lesion model of right coronary artery (RCA) was reconstructed by computed tomography angiography (CTA). The finite element method was used to simulate long-term implantation of overlapping resolute drug-eluting stent (DES). The overlap length was 3 mm. The entire procedure included the grasping and delivery of the stent, the placement of the distal stent and the proximal stent. During the virtual placement of the scaffold, the interaction between the stent and the stent, the stent and the blood vessel was analyzed by observing the changes of the stent and the vascular morphology and stress. The lumen cross-sectional area increased from the initial 1.4 mm2 to 6.5 mm2 after stenting, and the stenosis of blood vessels was well treated. In the stent overlap area, the distal stent located in the outer layer was more stressed than the proximal stent due to over-expansion. The stress of tube wall at overlap (0.64～0.81 MPa) was larger than that of non-overlap region (0.32-0.56 MPa). Over-dilatation of blood vessels in the overlap caused the lumen cross-sectional area not to be influenced by overlapping stent. The study shows that overlapping stents can make blood vessels unobstructed; and there were greater stress in the overlapping parts between the stent and vessel.
潘连强,吴广辉,刘玉倩,舒丽霞蔺嫦燕,蔡克强. 冠脉重叠支架虚拟置入的有限元分析[J]. 中国生物医学工程学报, 2018, 37(5): 576-583.
Pan Lianqiang, Wu Guanghui, Liu Yuqian, Shu Lixia, Lin Changyan,Cai Keqiang. Finite Element Analysis of Virtual Implantation of Coronary Overlapped Stent. Chinese Journal of Biomedical Engineering, 2018, 37(5): 576-583.
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