The Simulation of High Frequency Microwave Ablation Effect
Wu Xi1, Liu Baolin1*, Xu Binkai2
1Institute of Biothermal Technology, University of Shanghai for Science and Technology, Shanghai 200093, China; 2Accu Target Medi Pharma(Shanghai)Co., LTD, Shanghai 200120, China
Abstract：The permittivity of biological tissue can show the reaction on difference microwave frequency. Different tissue shows different permittivity under the same microwave frequency radiation, and the same tissue has different permittivity under different microwave frequency radiation. A numerical model reference to breast cancer was built to study the ablation difference between high frequency microwave (6 GHz, 12 GHz, 18 GHz) ablation and traditional microwave (915 MHz, 2 450 MHz) ablation and the clinical feasibility of high frequency microwave ablation was discussed. Simulation results showed that the 12 GHz microwave ablation caused the least damage to the normal tissue, which was 61.6% less than that caused by 2 450 MHz microwave ablation. The latter caused the most damage to the normal tissue when melting time was 600 s. The 6 GHz microwave ablation caused the least damage area in the normal tissue, which was 71.4% less than that caused by the 2 450 MHz microwave ablation. The latter caused the most damage to the normal tissue when the tumor tissue was damaged completely. When the temperature of tumor edge reached 52℃, the maximum difference of temperature was 111.2℃ in the 18 GHz microwave ablation, however, the difference of temperature was only 40.1℃ in the 2 450 MHz microwave ablation. Simulation results suggest that high frequency microwave ablation has advantages of material selection, less damage to the normal tissue, and more concentrated ablation area.
吴曦,刘宝林,徐彬凯. 高频率微波信号对微波消融效果影响的仿真研究[J]. 中国生物医学工程学报, 2017, 36(4): 449-455.
Wu Xi, Liu Baolin, Xu Binkai. The Simulation of High Frequency Microwave Ablation Effect. Chinese Journal of Biomedical Engineering, 2017, 36(4): 449-455.
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