可降解血管支架结构设计及优化的研究进展

doi:10.3969/j.issn.0258-8021.2019.03.014

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Abstract Due to the advantages of degradability and excellent biocompatibility, the biodegradable alloy stents, are expected to be the promising solution for the problems such as the restenosis of the permanent stents, the late stents thrombosis of drug eluting stents, leading the fourth generation of innovation in the field of the cardiovascular interventional therapy. However, insufficient scaffold performance and too short degradation time are the main limitations for the biodegradable stents in clinical application currently. To deal with these problems, stent design and optimization can be an effective method to improve scaffold performance of biodegradable stents and prolong their service time. Structure design and optimization of biodegradable stents is a complex process involving balance of different mechanical performances, hemodynamics and the changing of scaffold performance in corrosion environment. Therefore, in this article, the state-of-the-art design and optimization of the biodegradable stents were reviewed and the challenges and future research directions were pointed out.

Key words： biodegradable stent optimization design finite element analysis

Received: 17 August 2018

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R318

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	Articles by authors
	Peng Kun
	Li Jing
	Wang Sirui
	Xia Jun
	Qiao Aike

Cite this article:

Peng Kun,Li Jing,Wang Sirui, et al. Research Progress on the Structure Design and Optimization of Biodegradable Stents[J]. Chinese Journal of Biomedical Engineering, 2019, 38(3): 367-374.

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2019.03.014 OR http://cjbme.csbme.org/EN/Y2019/V38/I3/367

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