Research Progress of Protein Adsorption on Hydroxyapatite Surface
Fu Yakang1*, Zhang Kehong1, Weng Jie2, Liu Yaowen3
1Ya'an Polytechnic College, Ya'an 625000, Sichuan, China; 2Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China; 3School of Food, Sichuan Agricultural University, Ya’an 625014, Sichuan, China
Abstract This paper summarized the research progress of protein adsorption on hydroxyapatite (HAP) in the past 30 years, including adsorption mechanism, crucial factors and related application exploration. The adsorption mechanisms include electrostatic attraction, hydrogen bond and van der Waals force. The crucial factors include exposing crystal faces of HAP, specific surface area, concentration of PO43- and Ca2+, pH and temperature in the adsorption environment. In addition, this article introduced the application research of protein adsorption on HAP in the field of drug sustained-release carrier and bone tissue engineering scaffold. This review aimed to provide comprehensive introduction of advances for exploring the biological activity and special adsorption function design of HAP.
Fu Yakang,Zhang Kehong,Weng Jie, et al. Research Progress of Protein Adsorption on Hydroxyapatite Surface[J]. Chinese Journal of Biomedical Engineering, 2018, 37(6): 756-764.
[1] Guan Zhenyu,Huang Chaowei,Huang MC,et al. Controlling multi-function of biomaterials interfaces based on multiple and competing adsorption of functional proteins [J]. Colloids and Surfaces B: Biointerfaces,2017,149: 130-137. [2] Martínez-Ibáñez M,Murthy NS,Mao Yong,et al. Enhancement of plasma protein adsorption and osteogenesis of hMSCs by functionalized siloxane coatings for titanium implants [J]. Journal of Biomedical Materials Research Part B: Applied Biomaterials,2018,106 (3): 1138-1147. [3] Pang Dongwen,He Liyong,Wei Luxi,et al. Preparation of a beta-tricalcium phosphate nanocoating and its protein adsorption behaviour by quartz crystal microbalance with dissipation technique [J]. Colloids and Surfaces B: Biointerfaces,2018,162: 1-7. [4] Kang IG,Park CI,Lee H,et al. Hydroxyapatite microspheres as an additive to enhance radiopacity, biocompatibility, and osteoconductivity of poly (methyl methacrylate) bone cement [J]. Materials,2018,11 (2): 258. [5] Cheng Lijia,Yu Tian,Shi Zheng. Osteoinduction mechanism of calcium phosphate biomaterials in vivo: A review [J]. Journal of Biomaterials and Tissue Engineering,2017,7 (10): 911-918. [6] Langelier B,Wang Xiaoyue,Grandfield K. Atomic scale chemical tomography of human bone [J]. Scientific Reports,2017,7: 39958. [7] D'Elia NL,Gravina N,Ruso JM,et al. Albumin-mediated deposition of bone-like apatite onto nano-sized surfaces: Effect of surface reactivity and interfacial hydration [J]. Journal of Colloid and InterfaceScience,2017,494: 345-354. [8] Gholami F,Ismail S,Noor AFM. Development of carboxylated multi-walled carbon nanotubes and bovine serum albumin reinforced hydroxyapatite for bone substitute applications [J]. Journal of the Australian Ceramic Society,2017,53 (1): 117-127. [9] Xiao Dongqin,Guo Tailin,Yang Fei,et al. In situ formation of nanostructured calcium phosphate coatings on porous hydroxyapatite scaffolds using a hydrothermal method and the effect on mesenchymal stem cell behavior [J]. Ceramics International,2017,43 (1): 1588-1596. [10] Cleland TP,Vashishth D. Bone protein extraction without demineralization using principles from hydroxyapatite chromatography [J]. Analytical Biochemistry,2015,472: 62-66. [11] Niimi M,Masuda T,Kaihatsu K,et al. Virus purification and enrichment by hydroxyapatite chromatography on a chip [J]. Sensors and Actuators B: Chemical,2014,201: 185-190. [12] Roslan MAM,Mohamad MAN,Omar SM. High quality dna from peat soil for metagenomic studies a minireview on dna extraction methods [J]. Science,2017,1 (2): 1-6. [13] Tercinier L,Ye A,Anema S,et al. Characterisation of milk protein adsorption onto hydroxyapatite [J]. International Dairy Journal,2017,66: 27-33. [14] Zhang Ning,Gao Tianlin,Wang Yu,et al. Environmental pH-controlled loading and release of protein on mesoporous hydroxyapatite nanoparticles for bone tissue engineering [J]. Materials Science and Engineering: C,2015,46: 158-165. [15] Wang Jing,Zhang Huijie,Zhu Xiangdong,et al. Dynamic competitive adsorption of bone-related proteins on calcium phosphate ceramic particles with different phase composition and microstructure [J]. J Biomed Mater Res B Appl Biomater,2013,101 (6): 1069-1077. [16] Wu Fei,Lin DDW,Chang JH,et al. Effect of the materials properties of hydroxyapatite nanoparticles on fibronectin deposition and conformation [J]. Crystal Growth & Design,2015,15 (5): 2452-2460. [17] Wang Kefeng,Zhou Changchun,Hong Youliang,et al. A review of protein adsorption on bioceramics [J]. Interface Focus,2012,2 (3): 259-277. [18] Lee WH,Loo CY,Rohanizadeh R. A review of chemical surface modification of bioceramics: effects on protein adsorption and cellular response [J]. Colloids and Surfaces B: Biointerfaces,2014,122: 823-834. [19] Liao Chenyi,Xie Yun,Zhou Jian. Computer simulations of fibronectin adsorption on hydroxyapatite surfaces [J]. RSC Advances,2014,4 (30): 15759-15769. [20] Zhou Hailong,Wu Tao,Dong Xiuli,et al. Adsorption mechanism of BMP-7 on hydroxyapatite (001) surfaces [J]. Biochem Biophys Res Commun,2007,361 (1): 91-96. [21] Kandori K,Sawai S,Yamamoto Y,et al. Adsorption of albumin on calcium hydroxylapatite [J]. Colloids and Surfaces,1992,68 (4): 283-289. [22] Dos Santos E,Farina M,Soares G,et al. Surface energy of hydroxyapatite and β-tricalcium phosphate ceramics driving serum protein adsorption and osteoblast adhesion [J]. Journal of Materials Science: Materials in Medicine,2008,19 (6): 2307-2316. [23] Chen Xin,Wang Qi,Shen Jiawei,et al. Adsorption of leucine-rich amelogenin protein on hydroxyapatite (001) surface through-COO-claws [J]. The Journal of Physical Chemistry C,2007,111 (3): 1284-1290. [24] Dong Xiuli,Wang Qi,Wu Tao,et al. Understanding adsorption-desorption dynamics of BMP-2 on hydroxyapatite (001) surface [J]. Biophysical Journal,2007,93 (3): 750-759. [25] Kandori K,Saito M,Takebe T,et al. Adsorption of bovine serum albumin on synthetic carbonate calcium hydroxyapatite [J]. Journal of Colloid and InterfaceScience,1995,174 (1): 124-129. [26] Kandori K,Hamazaki H,Matsuzawa M,et al. Selective adsorption of acidic protein of bovine serum albumin onto sheet-like calcium hydroxyapatite particles produced by microreactor [J]. Advanced Powder Technology,2014,25 (1): 354-359. [27] Kandori K,Fudo A,Ishikawa T. Study on the particle texture dependence of protein adsorption by using synthetic micrometer-sized calcium hydroxyapatite particles [J]. Colloids and Surfaces B: Biointerfaces,2002,24 (2): 145-153. [28] 刘翠莲. 类骨羟基磷灰石的合成与应用 [D]. 杭州:浙江大学,2017:32-45. [29] Kandori K,Shimizu T,Yasukawa A,et al. Adsorption of bovine serum albumin onto synthetic calcium hydroxyapatite: influence of particle texture [J]. Colloids and Surfaces B: Biointerfaces,1995,5 (1): 81-87. [30] Zhuang Zhi,Aizawa M. Protein adsorption on single-crystal hydroxyapatite particles with preferred orientation to a (b)-and c-axes [J]. Journal of Materials Science: Materials in Medicine,2013,24 (5): 1211-1216. [31] 付亚康,周雪,肖东琴,等. 羟基磷灰石微纳结构对蛋白吸附的影响 [J]. 无机材料学报,2015,30 (5): 523-528. [32] Fernandez-Montes Moraleda B,San Roman J,Rodriguez-Lorenzo LM. Influence of surface features of hydroxyapatite on the adsorption of proteins relevant to bone regeneration [J]. J Biomed Mater Res A,2013,101 (8): 2332-2339. [33] Matsumoto T,Okazaki M,Inoue M,et al. Hydroxyapatite particles as a controlled release carrier of protein [J]. Biomaterials,2004,25 (17): 3807-3812. [34] Fujii E,Ohkubo M,Tsuru K,et al. Selective protein adsorption property and characterization of nano-crystalline zinc-containing hydroxyapatite [J]. Acta Biomaterialia,2006,2 (1): 69-74. [35] Kawachi G,Watanabe T,Ogata SI,et al. Protein adsorption on needle-shaped hydroxyapatite prepared by hydrothermal treatment of mixture composed of CaHPO4· 2H2O and β-Ca3 (PO4) 2 [J]. Journal of the Ceramic Society of Japan,2009,117 (1367): 847-850. [36] Yang Zhengpeng,Zhang Chunjing. Adsorption/desorption behavior of protein on nanosized hydroxyapatite coatings: A quartz crystal microbalance study [J]. Applied Surface Science,2009,255 (8): 4569-4574. [37] Smith DA,Connell SD,Robinson C,et al. Chemical force microscopy: applications in surface characterisation of natural hydroxyapatite [J]. Analytica Chimica Acta,2003,479 (1): 39-57. [38] Kawasaki K,Kambara M,Matsumura H,et al. A comparison of the adsorption of saliva proteins and some typical proteins onto the surface of hydroxyapatite [J]. Colloids & Surfaces B Biointerfaces,2003,32 (4): 321-334. [39] Yin Gang,Liu Zheng,Zhan Jin,et al. Impacts of the surface charge property on protein adsorption on hydroxyapatite [J]. Chemical Engineering Journal,2002,87 (2): 181-186. [40] Boix T,Gomez-Morales J,Torrent-Burgues J,et al. Adsorption of recombinant human bone morphogenetic protein rhBMP-2m onto hydroxyapatite [J]. Journal of Inorganic Biochemistry,2005,99 (5): 1043-1050. [41] Prigodich RV,O'Connor T,Coleman JE. Proton, cadmium-113, and phosphorus-31 NMR of osteocalcin (bovine.gamma.-carboxyglutamic acid containing protein) [J]. Biochemistry,1985,24 (22): 6291-6298. [42] Scudeller LA,Srinivasan S,Rossi AM,et al. Orientation and conformation of osteocalcin adsorbed onto calcium phosphate and silica surfaces [J]. Biointerphases,2017,12 (2): 02. [43] Roy ME,Nishimoto SK. Matrix Gla protein binding to hydroxyapatite is dependent on the ionic environment: calcium enhances binding affinity but phosphate and magnesium decrease affinity [J]. Bone,2002,31 (2): 296-302. [44] Wallin R,Cain D,Hutson SM,et al. Modulation of the binding of matrix Gla protein (MGP) to bone morphogenetic protein-2 (BMP-2) [J]. Thrombosis & Haemostasis,2000,84 (6): 1039-1044. [45] Wians F. The effects of magnesium and calcium on osteocalcin adsorption to hydroxyapatite [J]. Magnesium,1983,2: 83-92. [46] Hauschka PV,Carr SA. Calcium-dependent alpha-helical structure in osteocalcin [J]. Biochemistry,1982,21 (10): 2538-2547. [47] Sharpe JR,Sammons RL,Marquis PM. Effect of pH on protein adsorption to hydroxyapatite and tricalcium phosphate ceramics [J]. Biomaterials,1997,18 (6): 471-476. [48] Wassell DTH,Hall RC,Embery G. Adsorption of bovine serum albumin onto hydroxyapatite [J]. Biomaterials,1995,16 (9): 697-702. [49] Hlady V,Füredi-Milhofer H. Adsorption of human serum albumin on precipitated hydroxyapatite [J]. Journal of Colloid & Interface Science,1979,69 (3): 460-468. [50] Jr WJD,Miller IF. On the adsorption of serum proteins on polymer membrane surfaces [J]. Journal of Colloid & Interface Science,1973,44 (2): 221-241. [51] Dasgupta S,Bandyopadhyay A,Bose S. Zn and Mg doped hydroxyapatite nanoparticles for controlled release of protein [J]. Langmuir: The ACS Journal of Surfaces and Colloids,2010,26 (7): 4958. [52] Fu Hailuo,Rahaman MN,Day DE,et al. Hollow hydroxyapatite microspheres as a device for controlled delivery of proteins [J]. J Mater Sci Mater Med,2011,22 (3): 579-591. [53] Liu TY,Chen SY,Liu DM,et al. On the study of BSA-loaded calcium-deficient hydroxyapatite nano-carriers for controlled drug delivery [J]. Journal of Controlled Release,2005,107 (1): 112-121. [54] Xie Guangping,Sun Jiao,Zhong Gaoren,et al. Hydroxyapatite nanoparticles as a controlled-release carrier of BMP-2: Absorption and release kinetics in vitro [J]. J Mater Sci Mater Med,2010,21 (6): 1875-1880. [55] Kaito T,Myoui A,Takaoka K,et al. Potentiation of the activity of bone morphogenetic protein-2 in bone regeneration by a PLA-PEG/hydroxyapatite composite [J]. Biomaterials,2005,26 (1): 73-79. [56] Li Chunmei,Vepari C,Jin HJ,et al. Electrospun silk-BMP-2 scaffolds for bone tissue engineering [J]. Biomaterials,2006,27 (16): 3115-3124.
