1(Department of Biomedical Engineering,College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300072,China) 2(Academy of Medical Engineering and Translational Medicine, Tianjin University,Tianjin 300072,China)
Abstract Depressive disorder is a mental disorder with significant and persistent depressed mood as its main clinical feature. It has become a serious public health problem due to high prevalence rate, high recurrence rate, high suicide rate and high disability rate. In addition to the commonly used methods of medicine, psychology and physics for the treatment of depression, the transcranial direct current stimulation (tDCS), which developed in recent years, has been widely concerned in physical therapy because of its advantages of convenient use, fewer side effects, no need for anesthesia and economy. As a non-invasive brain stimulation technology, tDCS can stimulate the prefrontal cortex to regulate the excitability of the cerebral cortex through the skull, thus achieving the goal of improving depressive symptoms. To date, many research using tDCS in the treatment of depression have confirmed that tDCS has significant antidepressant efficacy and can improve the cognitive status of depressed patients. It has become a promising new treatment of depression. This paper reviewed the application and research progress of tDCS in the treatment of depression from the therapeutic mechanism, efficacy, safety operation, problems, and future development.
Zhang Lixin,Guo Dongyue,Liu Shuang, et al. The Research Progress of Transcranial Direct Current Stimulation in the Treatment of Depression[J]. Chinese Journal of Biomedical Engineering, 2018, 37(5): 616-624.
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