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| Synthesized Steady-State Visual Evoked Potentials Based on the Superposition Hypothesis |
| Gao Qian, Wang Tao, Zhan Changan |
| School of Biomedical Engineering,Southern Medical University,Guangzhou 510515,China |
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Abstract The aim of this study is to validate the superposition hypothesis that attempts to explain the stead-state visual evoked potentials (SSVEPs) in terms of linear convolution of the transient visual evoked potential (tVEP) and the stimulus train. From ten healthy adult subjects, we recorded the VEPs elicited by checkerboard pattern reversal at a series of stimulation rates (4, 7.1, 7.7, 8.3, 9.1, 10, 11.1, 12.5, 14.3, 16.7, 20, 25 rev/s). Then we synthesized the SSVEPs for each stimulation rate (7.1-25 rev/s) using the original tVEP recorded at 4 rev/s and its waveform transformations in amplitude and phase. We used the Hotelling T2 test to compare the synthesized SSVEPs (s-SSVEPs) with different tVEP templates and the recorded SSVEPs (r-SSVEPs) for each stimulation rate. The results showed that there was no significant difference between the synthetic SSVEPs and the recorded SSVEPs within the range of 7.1-9.1 rev/s stimulation rate based on the linear superposition principle when the actual recorded tVEP was used as a template (P>0.05), and there was a significant difference in the range of 10-25 rev/s stimulation rate (P<0.05), and the error between the two increases with the increase of the stimulus rate; and that the amplitude- and phase-transformed tVEPs can make no significant difference between the synthetic results and the measured reaction (P>0.05), the error between them was also decreased, and remained stable within the range of measured stimuli. These findings indicate that the tVEP waveforms vary with the stimulation rate, and that the validation of the superposition hypothesis requests the determination of the actual tVEP measurement at each stimulation rate.
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Received: 21 March 2016
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