多参数可调经颅微电流刺激仪的研制和基于脑电的效果评测

doi:10.3969/j.issn.0258-8021. 2015. 06.011

Abstract
Figure/Table
References (0)
Related Citation (15)

Download: PDF (3354 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Cranial electrotherapy stimulation (CES) has been widely used to treat the disorders as anxiety, depression, insomnia and chronic pain. In this work, we presented a cranial electrotherapy stimulation device that provided adjustable stimulation parameters such as wave pattern, repetition rate, pulse width and intensity. In order to prevent the difference on the stimulating current density due to the difference on the individual head impedance, a constant current density component was developed and used in the device. To evaluate the effect of the stimulation, we recruited 20 volunteers to carry out the experiment. The electroencephalography (EEG) technique and two-factor variance analysis method were used to map the changes pre- and post-CES. The results revealed that the interaction of the stimulation parameters and the pre- and post- CES is significant (P<0.01). Four kinds of waveforms (square wave, triangle wave, saw tooth wave, sine wave) can effectively improve the alphawave’s spectrum content in different degree. Furthermore, the presented sinusoid wave can significantly improve the percentage of the alpha-wave power spectrum (power spectrum ratio increased by more than 20%), the effectiveness of the device was demonstrated.

Key words： cranial electrotherapy stimulation electroencephalography alpha wave constant current density component

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	Yang Hu¹ Wang Yuduo¹Chen Xinhua²Yin Shengyong²Wu Tongning^3#*

Cite this article:

Yang Hu¹ Wang Yuduo¹Chen Xinhua²Yin Shengyong²Wu Tongning^3#*
. Development of Multi-Parameter Adjustable Cranial Stimulation Device and Effect Evaluation by EEG[J]. journal1, 2015, 34(6): 714-719.

URL:

http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021. 2015. 06.011 OR http://cjbme.csbme.org/EN/Y2015/V34/I6/714

［1］Kirsch DL, Smith RB. Cranial electrotherapy stimulation for anxiety, depression, insomnia, cognitive dysfunction, and pain［J］. Bioelectromagnetic Medicine, 2004: 727-740.
［2］Bastani A. Does anodal transcranial direct current stimulation enhance excitability of the motor cortex and motor function in healthy individuals and subjects with stroke: a systematic review and metaanalysis.［J］. Clinical Neurophysiology, 2012,123(4):644-657.
［3］Shealy CN, Cady RK, CulverVeehoff D, et al. Cerebrospinal fluid and plasma neurochemicals: response to cranial electrical stimulation［J］. Journal of Neurological and Orthopaedic Medicine and Surgery, 1998, 18(2): 94-97.
［4］Kennerly R. QEEG analysis of cranial electrotherapy: a pilot study［J］. Journal of Neurotherapy, 2004, 8: 112.
［5］Schroeder M, Barr R. Quantitative analysis of the electroencephalogram during cranial electrotherapy stimulation［J］. Clinical Neurophysiology, 2001, 112(11): 2075-2083.
［6］Bystritsky A, Moody T, Hembacher E, et al. Effects of cranial electrotherapy stimulation on brain activity in the resting state［J］. Controlled Clinical Trials, 1997, 13(1): 31-42.［7］Feusner J D, Madsen S, Moody T D, et al. Effects of cranial electrotherapy stimulation on resting state brain activity［J］. Brain and Behavior, 2012, 2(3): 211-220.
［8］杨启辉, 吴效明. 经颅微电流刺激对脑电波的增强效应［J］. 中国医学物理学杂志, 2011, 28(6): 3025-3027.
［9］Datta A, Dmochowski J P, Guleyupoglu B, et al. Cranial electrotherapy stimulation and transcranial pulsed current stimulation: a computer based highresolution modeling study［J］. Neuroimage,2013,65:280-287.
［10］余学飞. 现代医学电子仪器原理与设计［M］.第二版.广州:华南理工大学出版社，2007:233-235.
［11］刘光启, 康鑫, 卓子寒, 等. 多通道经颅电刺激仪的设计和研究［J］. 中国科技论文在线，2012:5.
［12］唐建. 人体表面肌电信号检测与神经肌肉电刺激仪的设计［D］. 长沙：中南大学, 2013.
［13］Wu Tongning, Shao Qing, Yang Lei. Simplified segmented human models for whole body and localised SAR evaluation of 20 MHz to 6 GHz electromagnetic field exposures［J］. Radiation Protection Dosimetry, 2013, 153(3):266-272.
［14］杜磊, 赵柏树, 陈笑风. 基于V/I转换电路的精密电流跟随器设计［J］. 微型机与应用, 2012,31(20): 20-21.
［15］Hyvrinen A, Karhunen J, Oja E. Independent Component Analysis［M］. New York: Wiley, 2001: 435-459.
［16］陈一心. 经颅微电流刺激疗法的研究进展［J］. 中国医药导刊, 2012, 14(6)：967-970.
［17］Stuss M, Donald T, Robert TK. Principles of Frontal Lobe Function［M］. New York: Oxford University Press Inc, 2002: 246-247.
［18］杨启辉. 抑郁症经颅微电流治疗系统［D］. 广州: 华南理工大学, 2012.
［19］Klimesch W. EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis［J］. Brain Research Reviews, 1999, 29(2): 169-195.
［20］李颖洁. 脑电信号分析方法及其应用［M］.北京:科学出版社, 2009:27-29.
［21］潘伟, 张珍花. 双因子等重复试验的方差分析在实证中的应用［J］. 统计与决策, 2007, 19(2): 19-21.
［22］张新. 脑电信号分析在认知功能中的研究［D］. 重庆:重庆大学, 2010.