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Development of Multi-Parameter Adjustable Cranial Stimulation Device and Effect Evaluation by EEG |
1 School of Information and Communication Engineering, Beijing Information Science and Technology University, Beijing 100101, China
2 Department of Hepatopancreatobiliary Surgery, The First Affiliated Hospital, Zhejiang University,Hangzhou 310003, China |
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Abstract Cranial electrotherapy stimulation (CES) has been widely used to treat the disorders as anxiety, depression, insomnia and chronic pain. In this work, we presented a cranial electrotherapy stimulation device that provided adjustable stimulation parameters such as wave pattern, repetition rate, pulse width and intensity. In order to prevent the difference on the stimulating current density due to the difference on the individual head impedance, a constant current density component was developed and used in the device. To evaluate the effect of the stimulation, we recruited 20 volunteers to carry out the experiment. The electroencephalography (EEG) technique and two-factor variance analysis method were used to map the changes pre- and post-CES. The results revealed that the interaction of the stimulation parameters and the pre- and post- CES is significant (P<0.01). Four kinds of waveforms (square wave, triangle wave, saw tooth wave, sine wave) can effectively improve the alphawave’s spectrum content in different degree. Furthermore, the presented sinusoid wave can significantly improve the percentage of the alpha-wave power spectrum (power spectrum ratio increased by more than 20%), the effectiveness of the device was demonstrated.
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