细菌生物膜厚度和面积对人耳听力的影响

doi:10.3969/j.issn.0258-8021. 2015. 04.006

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Abstract According to CT images of the right ear from a healthy volunteer, a 3D finite element model of the ear was established in PATRAN software by a selfcompiling program. Then NASTRAN software was used to make frequency response analysis for human ear finite element model. The model was carried through a frequency response analysis of normal ear structure and confirmed by the consistency in the calculated and experimental data after comparison. Combined with the clinical symptoms of otitis media, the effects of variation in thickness and area on hearing ability in the growth stage of bacterial biofilm were investigated. Results show that in the same frequency bands, the thickness variation of bacterial biofilm had the same regular pattern in the effects on hearing ability under different pressures. Thickness increase of bacterial biofilm decreased the stapes amplitude and stapes velocity in the same frequency band. The descend range of hearing ability was different in various frequency bands under the same pressure. The stapes amplitude and stapes velocity declined largely in low frequency band, the maximum value of the decline was 1.64 dB, and declined little in high frequency band. The maximum value of the decline was 1.04 dB. The area increase of bacterial biofilm decreased the stapes amplitude and stapes velocity in the same frequency band. The descend range of hearing ability was different in various frequency bands under the same pressure. The stapes amplitude and stapes velocity declined little in frequency band from 100-1 000 Hz, The maximum value of the decline was 0.18 dB, and declined largely in frequency band from 1 000 Hz to 10 000 Hz. The maximum value of the decline was 2.26 dB. In conclusion, the increase of thickness or area of bacterial biofilm caused the decline of hearing ability. The increase in the thickness caused more decline in the low frequency band than in the high frequency band, while the area increase caused opposite results.

Key words： human ear finite element model bacterial biofilm thickness area

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	Gan Chaosun Yao Wenjuan^*Guo Cuipin Ma Jianwei Chen Yiqiang

Cite this article:

Gan Chaosun Yao Wenjuan^*Guo Cuipin Ma Jianwei Chen Yiqiang. The Effects of Bacterial Biofilm Thickness and Area on Hearing[J]. journal1, 2015, 34(4): 421-428.

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021. 2015. 04.006 OR http://cjbme.csbme.org/EN/Y2015/V34/I4/421

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