Development of HighSpeed Medical Electrolyte Analyzer Based on Flow Injection
1(Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Department of Biomedical Engineering, Shenzhen University, Shenzhen 518000, China
2 Shenzhen New Industries Biomedical Engineering Co., Ltd, Shenzhen 518000, China
Abstract To meet the demand of automatic biochemical analyzer electrolyte test, a flow injection dynamic ion analysis method was proposed based on method and experiments in this paper. The new method took advantages of flow injection analysis (FIA) and ion selective electrode (ISE). With embedded technology, we developed a new electrolyte module and tested its accuracy, precision, stability and cross contamination. Experiment results showed that the relative deviation and cross contamination of K+、Na+ and Cl- were under 1%; the coefficient of variability respectively was 0.40%, 0.22% and 0.66% respectively; linearity error was -1.10%，-0.68% and -0.46% respectively; And stability was 1.11%, 0.76% and 1.39% respectively. The clinical results showed that the electrolyte module met the requirement of the clinical application. Compared with conventional electrolyte analyzer, this module can be applied together with automatic biochemical analysis instrument; moreover, its test speed reached 150 samples/h, which allows it to be used in the field of highspeed electrolyte analysis
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