原子力显微镜测量心肌细胞杨氏模量的研究现状

doi:10.3969/j.issn.0258-8021. 2014. 01.014

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Abstract Since the first atomic force microscopy (AFM) came into the world, it has been used in various fields, especially in cellular studies because of its own advantages. This article reviews not only AFM application in in measuring the Young’s modulus that is a parameter reflecting cells stiffness, but also the research progress of Young’s modulus in heart diseases. More researches reported the Young’s modulus increases along with the age and is related to heart diseases. It is helpful for understanding mechanical and pathologic changes in heart diseases, especially in heart failure and myocardial infarction in myocardial cells by determination of Young’s modulus.

Key words： Young’s modulus atomic forcefluorescence microscopy (AFM) myocardial cell mechanics property molecular biology

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	ZHU Ye ZHANG Yu Hui CHEN Ming^*

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ZHU Ye ZHANG Yu Hui CHEN Ming^*. Research Status of the Measurement for Young’s Modulus of Myocardial Cells Using Atomic Force Microscopy[J]. journal1, 2014, 33(1): 93-97.

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http://cjbme.csbme.org/EN/ 10.3969/j.issn.0258-8021. 2014. 01.014 OR http://cjbme.csbme.org/EN/Y2014/V33/I1/93

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