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| Current Status and Prospects of Diagnostic Methods for Diabetic Lower-Extremity ArterialDisease |
| Yang Yuxiang1#*, Shi Zhuangzhi1, Zhang Fu1, Zhang Linshan2, Zhu Yan3, Li Zhonglin4 |
1(School of Engineering and Design,Hunan Normal University, Changsha 410081,China)
2(Department of Endocrinology,Zhongshan Hospital,Fudan University,Shanghai 200032,China)
3(Department of Endocrinology,The First Affiliated Hospital of Hunan Normal University,Changsha 410005,China)
4(Xiangtan Diabetes Hospital,Xiangtan 411100,Hunan,China) |
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Abstract Diabetes mellitus (DM) lower extremity arterial disease (LEAD) is one of the main pathological factors leading to diabetic foot (DF) that is the most serious chronic complications of DM with the highest treatment cost. Therefore, timely diagnosis of LEAD is crucial to prevent the occurrence of DF. This paper summarized the LEAD diagnostic methods commonly used in clinic, including subjective evaluation, image detection and physiological parameter detection, and expounded the basic principles, advantages and disadvantages of these methods. In view of the current increasing demand for early diagnosis of LEAD, the research progress of microvascular disease (MVD) and local arterial pulse wave velocity (PWV) detection technology and their feasibility of clinical applications were summarized, which is expected to become a breakthrough for early diagnosis of asymptomatic LEAD in DM patients.
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Received: 16 May 2021
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Corresponding Authors:
*E-mail: yuxiang.yang@hunnu.edu.cn
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