基于时域光声信号的谱分析技术及其在生物医学领域的应用

doi:10.3969/j.issn.0258-8021.2022.04.009

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Abstract Time-domain photoacoustic (PA) signal measurement and spectral analysis technique is a non-invasive detection method that can provide the structural and functional information of biological tissue. Combining with the high contrast of optical modality and the high resolution of ultrasonic modality in deep tissue, PA signal data sets of target tissues under different wavelengths of light excitation are processed and analyzed. Compared with the conventional spectral detection, this technique is less susceptible to the limitations of the shape and morphology of the object to be measured and is not affected by the light scattering, therefore has a high sensitivity for the detection of deep tissues. In contrast to photoacoustic imaging, this technique does not require image reconstruction and focuses on achieving quantitative analysis. This article summarized the applications of time-domain PA signal spectral analysis technique in the detection of biological tissue, biological fluid, and biological exhaled gas, and reviewed the research progress and development directions of this technique around the improved experimental systems or different signal processing methods used in various studies.

Key words： time-domain photoacoustic signal spectrum analysis technology nondestructive testing quantitative analysis biomedical applications

Received: 09 June 2021

PACS:

R318

Corresponding Authors: ^*E-mail: wangyihan@xidian.edu.cn

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	Zheng Jiaxin
	Tian Rui
	Liu Mingqing
	Zan Kehua
	Wang Yihan
	Zhu Shouping

Cite this article:

Zheng Jiaxin,Tian Rui,Liu Mingqing, et al. Applications of Spectrum Analysis Technology Based on Time-Domain Photoacoustic Signalin Biomedical Field[J]. Chinese Journal of Biomedical Engineering, 2022, 41(4): 462-472.

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2022.04.009 OR http://cjbme.csbme.org/EN/Y2022/V41/I4/462

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