融合多特征脑电评估孤独症儿童

doi:10.3969/j.issn.0258-8021.2021.05.05

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Abstract Autism is a complex neurodevelopmental brain disease, early detection and accurate diagnosis are very important. This paper extracted power spectrum, entropy, bispectral coherence, and coherence from the EEG signals of 54 autistic and 50 normal children for analysis and research and conducted independent sample t test for each group of characteristics to analyze the differences between the groups. To improve the classification performance, the fusion of multi-feature EEG was proposed for the analysis, and the maximum correlation minimum redundancy algorithm was further used for the feature selection, and at last the support vector machine was used to establish the classification model. Results showed that the classification accuracy rate obtained by single feature classification was 64%, the sensitivity was 68.25%, the specificity was 65.25%, and the F1 score was 69.19%. The single feature was established and showed poor performance. When fusing multiple features for classification, the first 25 features were selected to build a model that had a high classification accuracy of 93.45%, the sensitivity was 91.73%, the specificity was 84.01%, and the F1 score was 92.54%, and the AUC reached 0.96, which had better performance than the single feature classification model. The results of this study provided a scientific and objective basis for the auxiliary diagnosis of autism, as well as a reliable reference for the later rehabilitation of autistic children.

Key words： autism electroencephalogram fusion machine learning classification

Received: 19 November 2020

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R318

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	Articles by authors
	Zhao Jie
	Jin Yajuan
	Zhang Zhiming
	Wan Lingyan
	Li Xiaoli
	Kang Jiannan

Cite this article:

Zhao Jie,Jin Yajuan,Zhang Zhiming, et al. Study on Multi-Feature Fusion of EEG to Evaluate Children with Autism[J]. Chinese Journal of Biomedical Engineering, 2021, 40(5): 550-558.

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2021.05.05 OR http://cjbme.csbme.org/EN/Y2021/V40/I5/550

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