高特质焦虑个体执行控制功能及其脑网络研究

doi:10.3969/j.issn.0258-8021.2021.03.03

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Abstract By using behavioral and complex network analysis methods, this study explored the executive control function and brain network characteristics of high trait anxiety (HTA) individuals. Sixteen HTA individuals (as subjects) and sixteen low trait anxiety (LTA) individuals (as controls) were asked to perform Simon spatial conflict task, while behavioral data (response time and accuracy rate) and 64-channel EEG signals were recorded simultaneously. The EEG data were analyzed by synchronous likelihood analysis, and the appropriate threshold value was selected to construct the brain network topology. The overall attribute parameters and node attribute parameters of the network were calculated. The behavior data and the attribute parameters of brain network were analyzed by ANOVA. Results showed that the conflict response time of HTA group was significantly longer than that of LTA group (641.29±72.11 vs 602.10±61.47, P< 0.05), and the response accuracy rate was significantly lower than that of LTA group (90.73±2.14 vs 95.62±1.52, P< 0.05). These results indicated that the efficiency of cognitive conflict response and their executive control ability decreased. Analysis of the brain network in beta rhythm showed that the frontal and parietal node degree of HTA group was significantly less than that of LTA group (P< 0.05), the clustering coefficient (0.5341±0.0813 vs 0.6243±0.0527) and global efficiency (0.0142±0.0037 vs 0.0185±0.0023) was significantly smaller than that of LTA group (P< 0.05), while the characteristic path length was significantly larger than that of LTA group (1.8057±0.0036 vs 1.4380±0.0117, P< 0.05). The results of high gamma rhythmic brain network were like those of beta rhythm. These results suggest that the execution control ability of conflict monitoring and conflict resolution in HTA individuals is reduced. The underlying mechanism is not only related to the impaired function of thefrontal-parietal execution control network, but also related to the weakening of the integration function and information transmission capacity of the brain network. Impaired function offrontal-parietal executive control network and decreased executive control ability are stable and inherent characteristics of HTA individuals.

Key words： trait anxiety cognitive conflict brain network executive control function Simon conflict

Received: 18 August 2020

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R318

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	Articles by authors
	Ji Shumei
	Bu Xinxin
	Xun Xingmiao
	Su Xinle
	Xu Quansheng

Cite this article:

Ji Shumei,Bu Xinxin,Xun Xingmiao, et al. Study on Executive Control Function and Brain Network inHigh Trait Anxiety Individuals[J]. Chinese Journal of Biomedical Engineering, 2021, 40(3): 272-279.

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2021.03.03 OR http://cjbme.csbme.org/EN/Y2021/V40/I3/272

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