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Algorithm Study of Real-Time Detection of Sleep Apnea-Hypopnea Event Based on Long-Short Term Memory-Convolutional Neural Network |
Yu Hui1, Wang Shuo1, Li Xinrui2, Deng Chenyang1, Sun Jinglai1, Zhang Lixin1, Cao Yuzhen1* |
1 Department of Biomedical Engineering, Tianjin University, Tianjin 300072, China; 2 Tianjin Hospital of ITCWM Nankai Hospital, Tianjin 300072, China |
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Abstract Sleep apnea and hypopnea syndrome (SAHS) is a potentially fatal disease as well as affects sleep quality. In order to balance the accuracy and time resolution of apnea and hypopnea (AH) event detection, this paper proposed a long-short term memory-convolutional neural network (LSTM-CNN) to predict AH event precisely, meanwhile an apnea-hypopnea index (AHI) estimation method based on event detection results was adopted to quantitatively assess the SAHS severity. The algorithm was tested using 54 subjects’ abdomen movement signals from National Heart Lung & Blood Institute. For over 900, 000 data fragments after preprocessing, the accuracy, sensitivity and specificity were 88.6%, 88.2% and 88.7% respectively. For the 54 subjects’ AHI, the Pearson correlation coefficient between estimated AHI and AHI scored from polysomnography (PSG) reached 0.98 and the Cohen's kappa coefficient for SAHS severity was 0.95. The results showed that this method not only realized a high-precision detection of AH event, but also accurately estimated the AHI and the severity of SAHS, therefore held the potential to be used for SAHS diagnosis before PSG or long-term monitoring of SAHS at home.
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Received: 19 April 2019
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