1(College of Pharmacy,Harbin Medical University,Harbin 150081,China) 2(Department of Pharmacy,the Second Affiliated Hospital of Harbin Medical University, Harbin 150081,China)
Abstract Myocardial infarction is a serious disease that threat human health. In the field of cardiovascular disease treatment, the lack of self-repairing ability of myocardial tissue is one of the challenges. Current therapeutic treatments for myocardial infarction are not able to recover the normal functions. Cardiac tissue engineering may be an important potential approach to repair damaged myocardial tissue. Tissue engineered materials can be used to deliver stem cells (bone marrow mesenchymal stem cells, embryonic stem cells, etc.), drugs or growth factors, and simulate extracellular matrix. Main investigations in this field include the delivery of stem cells and growth factors by scaffolds to repair myocardium, and have made remarkable progress. This article reviewed the recent application of tissue engineered materials in the field of cardiac tissue engineering as essential delivery carriers.
Chen Simin,Xie Guoping,Gao Yanan, et al. Application of Tissue Engineered Materials in the Repair of Myocardial Injury[J]. Chinese Journal of Biomedical Engineering, 2019, 38(6): 753-758.
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