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Chinese Journal of Biomedical Engineering  2019, Vol. 38 Issue (6): 753-758    DOI: 10.3969/j.issn.0258-8021.2019.06.014
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Application of Tissue Engineered Materials in the Repair of Myocardial Injury
Chen Simin1,2, Xie Guoping1, Gao Yanan1, Zhan Haihe1,2, Wu Linhua1,2*
1(College of Pharmacy,Harbin Medical University,Harbin 150081,China)
2(Department of Pharmacy,the Second Affiliated Hospital of Harbin Medical University, Harbin 150081,China)
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Abstract  Myocardial infarction is a serious disease that threat human health. In the field of cardiovascular disease treatment, the lack of self-repairing ability of myocardial tissue is one of the challenges. Current therapeutic treatments for myocardial infarction are not able to recover the normal functions. Cardiac tissue engineering may be an important potential approach to repair damaged myocardial tissue. Tissue engineered materials can be used to deliver stem cells (bone marrow mesenchymal stem cells, embryonic stem cells, etc.), drugs or growth factors, and simulate extracellular matrix. Main investigations in this field include the delivery of stem cells and growth factors by scaffolds to repair myocardium, and have made remarkable progress. This article reviewed the recent application of tissue engineered materials in the field of cardiac tissue engineering as essential delivery carriers.
Key wordstissue engineering materials      myocardial tissue      myocardial infarction      gels     
Received: 07 December 2018     
PACS:  R318  
Corresponding Authors: E-mail:wlhqkj@126.com   
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Chen Simin
Xie Guoping
Gao Yanan
Zhan Haihe
Wu Linhua
Cite this article:   
Chen Simin,Xie Guoping,Gao Yanan, et al. Application of Tissue Engineered Materials in the Repair of Myocardial Injury[J]. Chinese Journal of Biomedical Engineering, 2019, 38(6): 753-758.
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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2019.06.014     OR     http://cjbme.csbme.org/EN/Y2019/V38/I6/753
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