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Radiomics Review on Prediction and Prognosis of Liver Metastasis in Colorectal Cancer |
Su Xuan, Wang Yuanjun* |
(School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China) |
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Abstract Colorectal cancer is a cancer disease with high morbidity and mortality at home and abroad. Liver is a main target organ for colorectal cancer metastases. Predicting the occurrence of liver metastasis of colorectal cancer and real-time monitoring the prognostic response of patients is particularly critical to the diagnosis and treatment of the patients. Emerging radiomics offers possibilities for the accurate prediction of liver metastases and prognosis of colorectal cancer. In this paper, existing radiomics studies on colorectal cancer liver metastases (CRLM) were reviewed. Firstly, the clinical significance of CRLM and the limitations of the existing studies were introduced. Secondly, the radiomics analysis process of CRLM was described. Then, four research directions of radiomics on CRLM were reviewed, including predicting the histopathologic growth patterns (HGPs) in CRLM, predicting the hidden liver metastasis, prognosis assessment of liver metastases, and predicting the prognosis of survival in patients with liver metastasis. The latest research progress and challenges in each of the directions were described in detail. Finally, the future development trend of liver metastases radiomics of colorectal cancer was prospected.
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Received: 26 July 2021
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Corresponding Authors:
*E-mail: yjusst@126.com
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