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| Progress of Electromagnetic Detection and Imaging of Magnetic Nanoparticles |
| Zhu Jianjian1,2 , Yang Wenhui 1, Wei Shufeng1 , Wang Zheng1 , Lv Xing1* |
1 Institute of Electrical Engineering, University of Chinese Academy of Sciences, Beijing 100190, China
2 School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing 100049, China |
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Abstract Over the past decade, magnetic nanoparticles have been developed from the initial MRI contrast agent into a multi-functional material for diagnosis, targeted drug delivery and magneto-hyperthermia. Magnetic nanoparticle imaging (MPI) is a computer tomography technique to construct 3d images by detecting the magnetic properties of superparamagnetic nanoparticles injected into the blood vessels. In addition to angiography and stem cell tracking, magnetic nanoparticle imaging has a range of exciting potential biomedical applications such as real-time fluoroscopy, diagnosis and staging of cancer, in vivo inflammation imaging, temperature display, and functional molecular imaging. MPI attempts to obtain a tracer distribution of measured volumes in a more sensitive, faster and safer way based on existing contrast imaging techniques.In this paper, we first introduced the application of magnetic nanoparticles in molecular imaging and diagnosis, and then introduced the principle of electromagnetic detection of magnetic nanoparticles and the present situation of research as well as problems about system topologies and imaging reconstruction. At the end of this article, we proposed future important trend of the technology.
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Received: 12 December 2017
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