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EEG Response to Patients Own Name and Music in Severe Disorders of Consciousness |
1 College of Life Information Science & Instrument Engineering, Hangzhou Dianzi University, Hangzhou 310018, China
2 Rehabilitation Center, Wujing Hospital, Hangzhou 31400, China |
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Abstract Patient’s own name and music stimulations are the most commonly used means in clinical awaking therapy for patients in vegetative state (VS) and minimally conscious state (MCS). Therefore, to explore the mechanism of patient's brain EEG response to those different sound stimulations is of great value in clinical practice. In this paper, to compare the EEG responses to the different sound stimulations in the vegetative and minimally conscious states, 33 patients with severe consciousness disorder were selected in the study. Changes of EEG’s wavelet energy value before and after the stimulations lasting 60 s were calculated and statistically analyzed using wavelet transform method under 3 different sounds stimulations. Results showed that for MCS state, EEG energy change under patient’s own name stimulation ( mean value was 3.839) was greater than both other subject’s name stimulation (mean value was 1.609 with P<0.05 vs patient’s own name ) and Chinese classical music stimulation (mean value was 1.937 with P<0.05 vs patient’s own name); for VS state, it was also showed that EEG energy change under patients’s own name stimulation (mean values was 2.873 ) was greater than other subject’s name stimulation(mean value was 1.443 with P<0.05 vs patient’s own name) and Chinese classical music stimulation (mean value was 1.263 with P<0.05 vs patient’s own name). In conclusion, patients in MCS state or VS state, EEG energy change under patient‘s own name stimulation was greater than other subject’s name stimulation and Chinese classical music stimulation; Patients in MCS state produced a greater EEG response than those in VS state under the sound stimulations. This study provided a experimental foundation for the clinical awaking therapy by means of patients own name and music stimulations for patients in the vegetative and minimally conscious states.
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