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Research on Biomechanics Properties for BalloonExpandable Intracoronary Stents |
College of Mechanical Engineering, Inner Mongolia University of Technology, Hohhot 010051 China |
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Abstract In this paper we studied the mechanical properties of coronary stents with different connection bars, providing guidance for the design and development of the stent and interventional treatment. Solid Works was used to establish the three stent models with different connection bars which were called W-stent, S-stent, L-stent, crimp shell and balloon model. Hypermesh was used for meshing, ABAQUS was used to simulate their mechanical properties of radial recoil, axial shorting, expansion uniformity, radical bracing stiffness and the flexibility, at the same time verify the rationality of numerical simulation which present measure methods of bracing stiffness and bending stiffness which were based on radical uniform load and “fourpoint bending” measure technology. Results show that the mechanical properties of the three intracoronary stents are within the safe range. By comparing these stents, the biomechanics properties of A-stent are better; the radical bracing stiffness of B-stent is 3.34 N/mm, it so easily leads to injure the vascular wall because of its higher bracing stiffness; the axial shorting of C-stent is 8.25 %, because its axial shorting is larger, it is not conductive to the stent to find the correct position in the vessel; bending stiffness of A-stent and B-stent are as follows: 17.74 N/rad and 18.00 N/rad, their flexibility are larger. It’s proved that the numerical simulation results agree with the in vitro test results.
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[1]倪中华, 易红, 顾兴中. 载药纳米颗粒与血管支架自装配机理和方法[J]. 机械工程学报, 2005, 41(8):190-195.
[2]McGarry JP, O’Donnell BP, McHugh PE, et al. Analysis of the mechanical performance of a cardiovascular stent design based on micomechancial modeling[J]. Computational Materials Science, 2004, 31:421-438.
[3]程洁, 周啸, 李俐军, 倪中华. 冠脉支架的多功能体外力学性能测试装置及实验研究[J]. 东南大学学报(自然科学版), 2010, 40(2):341-345.
[4]郭飞飞,冯海全,江旭东,等.球囊扩张式冠脉支架耦合扩张变形机理研究[J].机械设计与研究,2012,28(3):30-33.
[5]Liang Dongke, Yang Dazhi, Qi Min, et al. Finite element analysis of stent implantation in a stenosed artery[J]. Key Engineering Materials, 2005, 288-289:571-574.
[6]王伟强. 冠状动脉支架力学行为有限元分析及其结构优化[D]. 大连:大连理工大学, 2005.
[7]王伟强, 梁栋科, 杨大智, 等. 冠脉支架系统瞬时膨胀过程的有限元分析及其优化设计[J]. 中国生物医学工程学报, 2005, 24(3):313-329.
[8]Duda SH, Wiskirchen J, Tepe G, et al. Physical properties of endovascular stents: an experimental comparison[J]. JVIR, 2000, 11:645-654.
[9]Dyet J F, Watts WG, Ettles DF, et al. Nicholson. Mechanical properties of metallic stents: how do these properties influence the choice of stent for specific lesions[J]. Cardiovasc Intervent, Radiol, 2000, 23:47-54.
[10]Matthieu DB. Finite element stent design [D]. Ghent:Ghent University, 2008.
[11]David Chua SN, Mac Donald BJ, Hashmi MSJ. Finite Element Simulation of Slotted Tube(stent) With the Presence of Plaque and Artery by Balloon Expansion[J]. Journal of Materials Processing Technology, 2004, 155-156:1772-1779.
[12]Wu W, Yang DZ, Qi M, et al. An FEA method to study flexibility of expanded coronary stents[J]. Journal of Materials Processing Technology, 2007, 447-450.
[13]Ormiston JA, Dixon SR, Webster M W, et al. Stent longitudinal flexibility: a comparison of 13 stent designs before and after balloon expansion[J]. Catheterization and Cardiovascular Interventions, 2000, 50:120-124.
[14]Takashima K, Kitoua T, Morib K, et al. Simulation and experimental observation of contact conditions between stents and artery models[J]. Medical Engineering & Physics, 2007, 29:326-335.
[15]Wang Weiqiang, Liang Dongke, Yang Dazhi, et al. Analysis of the transient expansion behavior and design optimization of coronary stents by finite element method[J].Journal of Biomechanics,2006, 39:21-32.
[16]冯海全, 江旭东, 胡志勇, 张烨. CoCr合金冠脉支架扩张变形的生物力学性能研究[J]. 功能材料, 2012, 2(43):182-186.
[17]张站柱, 乔爱科, 付文宇. 不同连接筋结构的支架治疗椎动脉狭窄的力学分析[J]. 医用生物力学, 2013, 28(1):44-49.
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