基于贝叶斯网络的临床信息模型检索方法研究:以HL7 V3为例

doi:10.3969/j.issn.0258-8021.2020.04.007

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (843 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Reuse of clinical informationmodels (CIMs) is important for the interoperability of electronic health records. Retrieving and identifying reusable CIMs is an efficient way. In this study,we used the HL7 V3 2017 normative edition released by HL7.org as an example and applied an extended four-layer Bayesian network to represent this CIM. We enriched the hierarchicalmessage description (HMD) layer based on the simple Bayesian network,and calculated the semantic similarity between them. Thereafter,the reusable CIMs were identified through probability inferencing in the network. In the evaluation,we designed three retrieval tasks (“encounter appointment”,“laboratory result“and “patient entity”),and used MAP (mean average precision),AP (average precision),accuracy at cut-off point as evaluation metrics. Finally,we constructed a four-layer Bayesian network with 3 428 nodes and 22 646 edges,from top to bottom,the number of nodes was 2 177,422,422,407 for data element layer,HMD layer,duplicate HMD layer and message type layer respectively. Results showed that the value of MAP was 0.382,and the average accuracy at 3^rd,5^th and 10^th cut-off points was 77.8%,60.0% and 46.7% respectively. Our method was capable to retrieve general models and domain reusable models,as well as semantic related objects (such as “reschedule appointment notification“object in “encounter appointment” retrieval task). In summary,our method could help improve reusability of HL7 V3 CIMs as well as international standardization of clinical information,meanwhile,it could be useful for the optimization of other CIMs retrieval.

Key words： HL7 V3 Bayesian network clinical information models information retrieval

Received: 04 November 2019

PACS:

R318

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	Huang Xiaoshuo
	Yang Lin
	Li Jiao

Cite this article:

Huang Xiaoshuo,Yang Lin,Li Jiao. A Method Based on Bayesian Network to Retrieve Clinical Information Models: A Case Study of HL7 V3[J]. Chinese Journal of Biomedical Engineering, 2020, 39(4): 440-448.

URL:

http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2020.04.007 OR http://cjbme.csbme.org/EN/Y2020/V39/I4/440

[1] Moreno-Conde A,Moner D,Dimas da Cruz W,et al.Clinical information modeling processes for semantic interoperability of electronic health records_ systematic review and inductive analysis[J].Journal of the American Medical Informatics Association,2015,22:925-934.
[2] Clinical Information Modeling Initiative.The main page of Clinical Information Modeling Initiative (CIMI) wiki[EB/OL].http://informatics.mayo.edu/CIMI/index.php/Main_Page,2015-02-22/2019-10-26.
[3] Monera D,Maldonadoa JA,Roblesb M.Archetype modeling methodology[J].Journal of Biomedical Informatics,2018,79:71-81.
[4] Moreno-Conde A,Austin T,Moreno-Conde J,et al.Evaluation of clinical information modeling tools[J].Journal of the American Medical Informatics Association,2016,23:1127-1135.
[5] Moreno-Conde A,Jódar-Sánchez F,Kalra D.Requirements for clinical information modelling tools[J].International Journal of Medical Informatics,2015,84:524-536.
[6] Pedersen R,Granja C,Marco-Ruiz L.The Value of Clinical Information Models and Terminology for Sharing Clinical information[C].The Eighth International Conference on eHealth,Telemedicine,and Social Medicine (eTELEMED 2016),2016:153-159.
[7] Goossen W,Goossen A,van der Zel M.Detailed clinical models:A review[J].Healthcare Informatics Research.2010,16(4):201-214.
[8] Health Level Seven International.Detailed Clinical Models[EB/OL].https://wiki.hl7.org/index.php?title=Detailed_Clinical_Models,2012-10-07/2019-10-26.
[9] Sharma DK,Solbrig HR,Tao Cui,et al.Building a semantic web-based metadata repository for facilitating detailed clinical modeling in cancer genome studies[J].Journal of Biomedical Semantics,2017,8(1):19.
[10] Goossen W.Model once,use multiple times:Reusing HL7 domain models from one domain to the other[J].Studies in Health Technology and Informatics,2004,107(Pt 1):366-370.
[11] Lopez DM,Blobel B.Enhanced semantic interoperability by profiling health informatics standards[J].Methods of Information in Medicine,2009,48(02):170-177.
[12] open Electronic Health Record Foundation.openEHR Clinical Knowledge Manager[EB/OL].https://openehr.org/ckm/,2019-10-26/2019-10-26.
[13] open Electronic Health Record China.Healthcare Modeling Collaboration[EB/OL].http://hmc.openehr.org.cn/#/archetype,2019-10-26/2019-10-26.
[14] Health Level Seven International.HL7 Version 3 Product Suite[EB/OL].http://www.hl7.org/implement/standards/product_brief.cfm?product_id=186,2017-01-30/2019-10-26.
[15] Health Level Seven中国委员会.HL7 中国委员会主页[EB/OL].http://www.hl7.org.cn,2019-09-18/2019-10-20.
[16] Yang Lin,Huang Xiaoshuo,Li Jiao.Discovering clinical information models online to promote interoperability of electronic health records:a feasibility study of openEHR[J].Journal of Medical Internet Research,2019,21(5):e13504.
[17] Noumeir R.Active Learning of the HL7 Standard[J].Journal of Digital Imaging,2019,32:354-361.
[18] Priya J.Tool-assisted healthcare knowledge to HL7 message translation[D].Hamilton:McMaster University,2009.
[19] 中共中央国务院.“健康中国2030”规划纲要[EB/OL].http://www.nhc.gov.cn/guihuaxxs/s3586s/201610/21d120c917284007ad9c 7aa8e9634bb4.shtml,2016-10-25/2019-10-26.
[20] 国家卫生健康委员会规划与信息司.全国医院信息化建设标准与规范(试行)[EB/OL].http://www.nhc.gov.cn/ewebeditor/uploadfile/2018/04/20180413162542120.pdf,2016-10-25/2019-10-26.
[21] 李保罗,冯东雷,李敬东,等.HL7的现状、应用与进展[J].中国数字医学,2013,8(3):3-7,11.
[22] 段会龙.医学信息相关标准分析[J].中国生物医学工程学报,2008,27(02):206-212.
[23] 黎亮,张君雁.医疗数据整合模式的研究[J].中国生物医学工程学报,2010,29(2):207-211.
[24] 吕旭东.一种电子病历系统体系结构及其关键技术[J].中国生物医学工程学报,2008,27(2):42-48.
[25] 沈剑峰,汪崴,杜平,等.基于卫生信息平台的电子病历信息共享研究和实现[J].中国生物医学工程学报,2013,32(4):504-507.
[26] 国家卫生计生委办公厅.关于下达2016年卫生标准制定修订项目计划的通知[EB/OL].http://www.nhc.gov.cn/fzs/s3581p/201601/980df9c0f7bf4266a68ed2bde432b2eb.shtml,2016-01-22/2019-10-26.
[27] 国家卫生计生委统计信息中心.国家医疗健康信息区域(医院)信息互联互通标准化成熟度测评方案(2017年版)[EB/OL].http://www.nhc.gov.cn/mohwsbwstjxxzx/s8553/201709/06ac0b5228674ce487405de8e939d40b.shtml,2017-09-05/2019-10-26.
[28] 缪姝妹,景慎旗,张小亮,等.大型三甲医院临床数据中心系统的建设与应用[J].中国数字医学,2016,11(10):5-8.
[29] 张超,徐金建,计虹.基于集成平台的实验室信息系统改进的研究与应用[J].中国数字医学,2019,14(3):114-116.
[30] Worden R,Scott P.Simplifying hl7 version 3 messages[J].Studies in Health Technology &Informatics,2011,169(1):709-713.
[31] Browne E.openEHR Archetypes for HL7 CDA Documents[EB/OL].https://openehr.atlassian.net/wiki/spaces/stds/pages/5373955/,2008-11-04/2019-10-26.
[32] Priya J.Tool-assisted healthcare knowledge to HL7 message translation[D].Hamilton:McMaster University,2009.
[33] Rotmensch M,Halpern Y,Tlimat A,et al.Learning a health knowledge graph from electronic medical records[J].Scientific Reports,2017,7(1):5994.
[34] Acid S,de Campos LM,Fernandez-Luna JM.An information retrieval model based on simple Bayesian networks[J].International Journal of Intelligent Systems,2003,18(2):251-265.
[35] Garrouch K,Omri MN.Bayesian network based information retrieval model[C]//International Conference on High Performance Computing &Simulation.Genoa:IEEE,2017:193-200.
[36] Health Level Seven International.Health level 7 fast health interoperability resources release 4[EB/OL].http://hl7.org/fhir/?utm_referrer=http%3A%2F%2Fhl7.org%2Fimplement%2Fstandards%2Fproduct_brief.cfm%3Fproduct_id%3D491.2020-01-01/2020-01-01.
[37] The ART-DECOR Expert Group.Advanced requirements tooling (ART) DÉCOR open tools[EB/OL].http://art-decor.org/art-decor/home.2019-12-24/2019-12-24.
[38] Open Mapping Software Ltd.The openMapping software[EB/OL].http://www.openmapsw.com/,2019-12-24/2019-12-24.