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Chinese Journal of Biomedical Engineering  2018, Vol. 37 Issue (5): 593-605    DOI: 10.3969/j.issn.0258-8021.2018.05.011
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Measurements of Wall Shear Stress for Blood Vessel and its Progress in Clinical Research
Du Yigang1,Liu Dejie1,Shen Yingying1,Zhu Lei1,He Xujin1,Chen Siping2#*
1(Shenzhen Mindray Bio-Medical Electronics Co.Ltd., Shenzhen 518057, Guangdong, China)
2(National\|Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory forBiomedical Measurements and Ultrasound Imaging,School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060, Guangdong, China)
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Abstract  This paper summarized different methods for measuring wall shear stress (WSS) of the blood vessel. The methods include using PC-MRI (phase contrast magnetic resonance imaging), PC-MRI with CFD (computational fluid dynamics), CT (computed tomography), IVUS (intravascular ultrasound), conventional ultrasound, ultrasound vector flow imaging and UIV/PIV (ultrasound/particle image velocimetry) for measuring blood flow velocities and then calculate the WSS based on the measured velocities. An important parameter, blood viscosity,was presented in the paper for calculating WSS.The calculation of 3D vector WSS and WSS related clinical parameters were summarized and discussed. Clinical studies of WSS for carotid artery, aorta, coronary artery, brachial artery and femoral artery have been presented in the paper and 3 major concepts for WSS were summarized from references.
Key wordswall shear stress (WSS)      viscosity      atherosclerosis      magnetic resonance imaging      ultrasound vector flow imaging     
Received: 06 March 2018     
PACS:  R318  
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Du Yigang
Liu Dejie
Shen Yingying
Zhu Lei
He Xujin
Chen Siping
Cite this article:   
Du Yigang,Liu Dejie,Shen Yingying, et al. Measurements of Wall Shear Stress for Blood Vessel and its Progress in Clinical Research[J]. Chinese Journal of Biomedical Engineering, 2018, 37(5): 593-605.
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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2018.05.011     OR     http://cjbme.csbme.org/EN/Y2018/V37/I5/593
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