A Methodological Review on Morphometric Parameters of Micro-CT Trabecular Bone Images
Liu Rong1#, Guo Xinlu1, Zhang Yakun1, Wang Yongxuan2*
1Department of Biomedical Engineering, Dalian University of Technology, Dalian 116024, Liaoning, China 2Affiliated Zhongshan Hospital of Dalian University,Dalian 116001,Liaoning,China
Abstract：Osteoporosis is one of the hotspots in the orthopedic field. Some studies have revealed that not only the changes in bone mineral density (bone mass) but also changes of trabecular bone structure are pathogenic factors. The trabecular bone morphometric analysis is one kinds of important method to study trabecular bone structure change. In this paper, some methods to calculate the trabecular bone morphometric parameters based on Micro-CT images were introduced, such as trabecular anisotropy, connectivity, structure model index, texture and other trabecular bone characteristics. Meanwhile, some examples were given to summarize the applicability, pros and cons of the trabecular bone morphometric parameters to provide evidence for the effective evaluation of osteoporosis and drug treatment.
刘蓉, 郭新路, 张亚坤, 王永轩. 骨小梁Micro-CT图像形态计量学参数计算方法综述[J]. 中国生物医学工程学报, 2018, 37(2): 237-246.
Liu Rong, Guo Xinlu, Zhang Yakun, Wang Yongxuan. A Methodological Review on Morphometric Parameters of Micro-CT Trabecular Bone Images. Chinese Journal of Biomedical Engineering, 2018, 37(2): 237-246.
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