间充质干细胞与组织工程血管

doi:10.3969/j.issn.0258-8021.2013.02.014

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摘要间充质干细胞在再生医学领域中具有重要的应用价值，其增殖能力强，免疫原性低，具有良好的分化潜能，是理想的组织工程血管种子细胞。本文系统总结了应用间充质干细胞构建组织工程血管的研究进展，介绍了间充质干细胞分离纯化和鉴定方法，分类阐述了间充质干细胞构建组织工程血管的几种方法，并探讨了其优缺点。

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	赵亮李敏^*

关键词 ：间充质干细胞, 组织工程血管, 体内构建, 体外构建

Abstract：Mesenchymal stem cell has showed important application potentials in the field of regenerative medicine. The stem cells have low immunogenicity, good differentiation potential and proliferation ability, which make them become ideal seed cells in tissue engineering vessel. This paper introduced research progress of applying mesenchymal stem cells to construct tissue engineering vessel, particularly describing separation purification and identification methods of mesenchymal stem cells. The paper also elaborated methods of constructing tissue engineering vessel with mesenchymal stem cells, and discussed the advantages and disadvantages of each method.

Key words： mesenchymal stem cells tissue engineering vessel construction in vivo construction in vitro

基金资助:福建省科技厅重点项目（2010Y0020）；国家级大学生创新创业训练计划（201210394016）

引用本文:

赵亮李敏^*. 间充质干细胞与组织工程血管[J]. 中国生物医学工程学报, 2013, 32(2): 220-225.
ZHAO Liang LI Min^*. Mesenchymal Stem Cell and Tissue Engineering Vessel. journal1, 2013, 32(2): 220-225.

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http://cjbme.csbme.org/CN/10.3969/j.issn.0258-8021.2013.02.014 或 http://cjbme.csbme.org/CN/Y2013/V32/I2/220

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