Abstract：With acceleration of population aging and urbanization, the number of patients with cardiovascular diseases has gradually increased. Development of cardiovascular implantable devices have attracted increasing attentions in recent years. The high risk of thrombosis is a major factor limiting the application of cardiovascular implanted devices, that is why it is so important to construct anticoagulant coatings on the surface of cardiovascular implanted devices. In this review, we summarized the research progress of anticoagulant coating construction methods in both domestic and foreign researches, analyzed and discussed the conventional and latest anticoagulation strategies from the aspects of physical, chemical and biological methods. Existing problems and prospects of anticoagulation coating construction were also discussed.
雷少瑾, 郑毅, 史杰, 董云生, 王淑芳. 抗凝血涂层构建方法及发展前景[J]. 中国生物医学工程学报, 2024, 43(3): 377-384.
Lei Shaojin, Zheng Yi, Shi Jie, Dong Yunsheng, Wang Shufang. The Technologies and Perspectives of Anticoagulant Coating. Chinese Journal of Biomedical Engineering, 2024, 43(3): 377-384.
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