Experimental Study on Effective Microwave Ablation Volume Model
1 Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China
2 The Affiliated Tumor Hospital of Xiangya Medical School of Central South University / Hunan Provincial Tumor Hospital, Changsha 410013, China
Abstract：Temperature variation in ablated area and effective ablation volume are very important parameters for microwave ablation treatment. In order to provide reference for realtime assessment of ablation efficacy, in vitro porcine liver experiments were carried out to monitor tissue temperature and build effective microwave ablation volume models in this work. Microwave power of 40~70 W and ablation time of 300~600 s were chosen to perform total 112 microwave ablations. The microwave power of 70 W was used in the first group of experiments and temperature changes at sites 5, 10, 15 and 20 mm away from microwave antenna were recorded in realtime during ablation. In the second group of experiments, different combinations of power and time produced a series of data of short axis, long axis and volume. Results showed that the increase of temperature near the microwave antenna was more rapid. Temperature rise at 5 mm away from the antenna was 10 times faster than that at 20 mm away. Volume data of the ablation area was analyzed using 1stopt to build experimental models for the short axis, long axis and volume of the ablation zone. Consequently, the monitoring of temperature and utilization of effective volume models will contribute to the microwave ablation surgical planning and realtime ablation efficacy assessment.