Research on the Applications of Electrochemical Sensor Modified with Layer-by-Layer Self-Assembly Films
Shi Gaofan1,2, Lin Xiangde2*, Liu Huajie3, Zhang Mengmeng2, Xia Pengpeng2, Liu Sisi2, Chen Yuzhu2, Zeng Dongdong2,3*
1(School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China) 2(The Medical Instrumentation College, Shanghai University of Medicine & Health Sciences, Shanghai 201318, China) 3(School of Chemical Science and Engineering, Tongji University, Shanghai 200092, China)
Abstract：Electrochemical sensors are widely used in the detection of various biochemical substances due to their excellent sensitivity, detection limit, selectivity and response rate. The electrode acts as a sensitive element of electrochemical sensors, and a reasonable surface modification coating is particularly important to improve the detection accuracy and stability of the sensor. The layer-by-layer self-assembly technology is widely used in the field of electrochemical sensors, because it is able to construct three-dimensional material system with nanometer precision controllable parameters by alternately depositing interacting substances on the substrate. In this paper,we summarized assembly materials (including polyelectrolytes and nanoparticles, etc.)the film driven force (including electrostatic interaction, covalent bond, hydrogen bond, etc.), performance optimization and technical improvement of the layer-by-layer self-assembly technologies were summarized. In addition, electrochemical sensors modified by layer-by-layer self-assembly films of nanomaterials and their applications in biomarker detection, air monitoring, metal ion detection were introduced.
施高凡, 林祥德, 柳华杰, 张蒙蒙, 夏鹏鹏, 刘思思, 陈玉竹, 曾冬冬. 层层自组装薄膜改性的电化学传感器应用[J]. 中国生物医学工程学报, 2023, 42(3): 370-384.
Shi Gaofan, Lin Xiangde, Liu Huajie, Zhang Mengmeng, Xia Pengpeng, Liu Sisi, Chen Yuzhu, Zeng Dongdong. Research on the Applications of Electrochemical Sensor Modified with Layer-by-Layer Self-Assembly Films. Chinese Journal of Biomedical Engineering, 2023, 42(3): 370-384.
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