Abstract：For the clinical diagnosis of AF with premature ventricular contraction (AF with PVC) and AF with aberrant ventricular conduction (AF with AVC), there are no recognized standards, which make it very difficult for a cardiologist to accurately discriminate the two diseases. This paper intends to develop a highaccuracy calculation method to discriminate between these two types of diseases. Methods：By analyzing clinical features of AF with PVC and AF with AVC, we confirmed the ratio between coupling interval and compensatory pause as the identifiable characteristic parameter. The electrocardiogram (ECG) signal that to be detected was preprocessed, then we located QRST characteristic waves during each cardiac cycle of ECG signal. On this basis, we identified the wide freak QRS complexes, extract the two adjacent RR intervals corresponding to the coupling interval and compensatory pause in a wide freak QRS complex, and calculate their ratio. After comparing with a given discrimination threshold, the types of diseases were judged. Results： The 10 record data for the algorithm validation were downloaded from the MITBIH Arrhythmia Database, which include 4 026 and 949 beats of atrial fibrillation with premature ventricular contraction and with aberrant ventricular conduction, a total of 4 975 beats.
For the mixed data containing AF with PVC and AF with AVC, the sensitivity and the positive predictive value of proposed method to discriminate AF with PVC reached 9315% and 9830% respectively, which are better than that of traditional methods. Conclusions：The ratio between the coupling interval and compensatory pause can take the place of coupling interval, which is commonly used to discriminate between AF with PVC and AF with AVC at present. This work provides guidance in the diagnostic accuracy of AF with PVC and AF with AVC.
钱梦瑶 饶妮妮#* 刘定宇 杨阳 张莹 万永利. 房颤伴室性早博与房颤伴差异性传导的量化鉴别方法研究[J]. 中国生物医学工程学报, 2015, 34(2): 129-135.
Qian Mengyao Rao Nini#* Liu Dingyu Yang Yang Zhang Ying Wan Yongli. Study on the Quantification for Discrimination of Atrial Fibrillation with Premature Ventricular Contraction and Aberrant Ventricular Conduction. journal1, 2015, 34(2): 129-135.
