低温保存对生物样本及其生物大分子的影响

doi:10.3969/j.issn.0258-8021.2017.05.015

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Abstract The role of biobanking in modern medical research is becoming more and more important with the endless achievements based on biobanks, which greatly promotes the development of translational medicine. The qualities of the specimens from biobanks have a great effect on the reliability of the researches. So how to guarantee the qualities of the samples is the key of the research on biobanks. Cryopreservation technology can maintain the viability of the specimens, which will play a significant role in the development of biobanks if preserving the complete molecular information and maintaining the viabilities of the specimens. The damage which freezing or cold brings to the specimens (especially to the biological macromolecules of the samples) and how to reduce these damages are reviewed in this article.

Key words： biobank cryopreservation cold injury

Received: 25 October 2016

PACS:

R318

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	Articles by authors
	Liang Wei
	Wang Meixia
	Liu Baolin

Cite this article:

Liang Wei,Wang Meixia,Liu Baolin. The Effect of Cryopreservation on Biospecimens and Biomacromolecules[J]. Chinese Journal of Biomedical Engineering, 2017, 36(5): 615-621.

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2017.05.015 OR http://cjbme.csbme.org/EN/Y2017/V36/I5/615

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