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Progress in the Preparation of Fluorescence-Encoded Microspheres |
Li Yan1, Luo Cheng1*, Wu Daocheng2 |
1 (School of Medicine, Yichun University, Yichun 336000,Jiangxi, China) 2(Key Laboratory of Biomedical Information Engineering of Education Ministry, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, China) |
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Abstract Suspension array is a promising platform for multiplex analyses with broad applications in science research and clinical diagnosis. As one of the key components for the suspension array, fluorescence-encoded microspheres have received much attention and a lot of achievements have been made. In this review, the analysis pattern and applications of suspension array were introduced, and recent advances in the fluorescence-encoded microspheres were summarized according to the classification of preparationmethods including swelling method, layer-by-layer (LBL) self-assembly, embedding in microspheres, microfluidic techniques and membrane emulsification. Current challenges and future directions of fluorescence-encoded microspheres were also outlined.
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Received: 20 July 2016
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