最大长度序列诱发听性脑干反应的线性与非线性成分引出率和稳定性分析

doi:10.3969/j.issn.0258-8021.2016. 02.004

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Abstract The auditory system is treated as a linear system to record the conventional auditory brainstem response (cABR). An advanced stimulation technique using maximum length sequence (MLS) is introduced to establish a Volterra series expansion model, and to obtain the representation of ABR components in response to individual and multiple stimulation. Under this way, the ABR is called MLS-ABR. To date, the literature report on nonlinear MLS-ABR has been limited due to the acquisition and technique difficulty. This study was aiming to investigate nonlinear ABRs using a MLS stimulation of 9^thdegree on 11 normal human adults. The MLS-ABR featured waves 1, 3, and 5, corresponding to cABR, waves I, II and V were selected for further analysis. The results demonstrated a clear morphology of the firstorder and secondorder kernel slices (VS1 and VS21), which reflect the linear and nonlinear components of ABR, with relative high elicitations (> 80 %) of the selected featured waves for both slices, and particularly, the wave 5 exhibited strong nonlinear effects. The variable coefficients were used to quantify the latency stability of the featured waves in comparison with that of cABRs. The results presented that the linear components in MLSABR (the variable coefficients of wave 1, 3, 5 were 5.17, 3.70, 2.00, respectively) was more stable than cABR (the variable coefficients of wave I, III, V were 6.54, 3.70, 2.87), This study validated that nonlinearity of ABR could be presented by MLS method, and demonstrated the fundamental nonlinear characteristics of MLSABRs, providing a reference for future study.

Key words： maximum length sequence evoked auditory brainstem response nonlinear component Volterra series nonlinear system

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	Huang Zhaohui Lin Lin Wang Tao^*

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Huang Zhaohui Lin Lin Wang Tao^*. Analysis on Elicitation and Stability of Linear and Nonlinear Components in Maximum Length Sequence Evoked Auditory Brainstem Response[J]. journal1, 2016, 35(2): 148-154.

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http://cjbme.csbme.org/EN/10.3969/j.issn.0258-8021.2016. 02.004 OR http://cjbme.csbme.org/EN/Y2016/V35/I2/148

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